Literature DB >> 2425571

Endotoxins release histamine by complement activation and potentiate bacteria-induced histamine release.

S Norn, C Jensen, B T Dahl, P Stahl Skov, L Baek, H Permin, J O Jarløv, H Sørensen.   

Abstract

The histamine-releasing capability of bacterial lipopolysaccharides (LPS) was examined in human leukocyte suspensions. LPS alone did not release histamine, but it was found to enhance the histamine release caused by bacteria in basophils from persons sensitized to these bacteria. In the presence of serum, LPS was able to release histamine through complement activation. It is speculated that endotoxins reinforce release of histamine caused by bacteria in persons sensitized to these microorganisms, and a direct mediator release via complement activation might play a role in septic conditions.

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Year:  1986        PMID: 2425571     DOI: 10.1007/bf01988007

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  8 in total

1.  Bacteria-induced histamine release. Examination of the bacterial cell wall components peptidoglycan, teichoic acid and protein A.

Authors:  S Norn; P Stahl Skov; C Jensen; F Espersen; J O Jarløv
Journal:  Agents Actions       Date:  1985-04

2.  Activation of the classical and properdin pathways of complement by bacterial lipopolysaccharides (LPS).

Authors:  D C Morrison; L F Kline
Journal:  J Immunol       Date:  1977-01       Impact factor: 5.422

3.  Intrinsic asthma and bacterial histamine release via lectin effect.

Authors:  S Norn; P S Skov; C Jensen; C Koch; H Permin; T C Bøg-Hansen; H Løwenstein; N Høiby
Journal:  Agents Actions       Date:  1983-04

4.  Studies on hypersensitivity to bacterial antigens in intrinsic asthma.

Authors:  C Koch; P Andersen; J Boëtius Hertz; N Høiby; E Kappelgaard; N E Møller; S Norn; M Pedersen; P S Petersen; P Stahl Skov; P Tønnesen
Journal:  Allergy       Date:  1982-04       Impact factor: 13.146

5.  A simplified method for measuring basophil histamine release and blocking antibodies in hay fever patients. Basophil histamine content and cell preservation.

Authors:  P S Skov; S Norn
Journal:  Acta Allergol       Date:  1977-06

6.  Quantitative and qualitative estimations of IgE bound to basophil leukocytes from hay fever patients.

Authors:  P S Skov; H Permin; H J Malling
Journal:  Scand J Immunol       Date:  1977       Impact factor: 3.487

7.  Bacterial histamine release by immunological and non-immunological lectin-mediated reactions.

Authors:  C Jensen; S Norn; P Stahl Skov; F Espersen; C Koch; H Permin
Journal:  Allergy       Date:  1984-07       Impact factor: 13.146

8.  Staphylococcus aureus peptidoglycan induces histamine release from basophil human leukocytes in vitro.

Authors:  F Espersen; J O Jarløv; C Jensen; P S Skov; S Norn
Journal:  Infect Immun       Date:  1984-12       Impact factor: 3.441

  8 in total
  3 in total

1.  Phagocytic and tumor necrosis factor alpha response of human mast cells following exposure to gram-negative and gram-positive bacteria.

Authors:  M Arock; E Ross; R Lai-Kuen; G Averlant; Z Gao; S N Abraham
Journal:  Infect Immun       Date:  1998-12       Impact factor: 3.441

2.  Staphylococcus aureus and influenza A virus stimulate human bronchoalveolar cells to release histamine and leukotrienes.

Authors:  P Clementsen; H Bisgaard; M Pedersen; H Permin; E Struve-Christensen; N Milman; B Nüchel-Petersen; S Norn
Journal:  Agents Actions       Date:  1989-04

3.  Virus enhances histamine release from human basophils.

Authors:  P Clementsen; C B Jensen; J O Jarløv; C Hannoun; S Norn
Journal:  Agents Actions       Date:  1988-04
  3 in total

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