Literature DB >> 24254230

Small RNAs, big impact: small RNA pathways in transposon control and their effect on the host stress response.

Bayly S Wheeler1.   

Abstract

Transposons are mobile genetic elements that are a major constituent of most genomes. Organisms regulate transposable element expression, transposition, and insertion site preference, mitigating the genome instability caused by uncontrolled transposition. A recent burst of research has demonstrated the critical role of small non-coding RNAs in regulating transposition in fungi, plants, and animals. While mechanistically distinct, these pathways work through a conserved paradigm. The presence of a transposon is communicated by the presence of its RNA or by its integration into specific genomic loci. These signals are then translated into small non-coding RNAs that guide epigenetic modifications and gene silencing back to the transposon. In addition to being regulated by the host, transposable elements are themselves capable of influencing host gene expression. Transposon expression is responsive to environmental signals, and many transposons are activated by various cellular stresses. TEs can confer local gene regulation by acting as enhancers and can also confer global gene regulation through their non-coding RNAs. Thus, transposable elements can act as stress-responsive regulators that control host gene expression in cis and trans.

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Year:  2013        PMID: 24254230     DOI: 10.1007/s10577-013-9394-4

Source DB:  PubMed          Journal:  Chromosome Res        ISSN: 0967-3849            Impact factor:   5.239


  147 in total

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Authors:  B McClintock
Journal:  Science       Date:  1984-11-16       Impact factor: 47.728

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3.  DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes.

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Journal:  Genes Dev       Date:  2008-04-01       Impact factor: 11.361

4.  CENP-B cooperates with Set1 in bidirectional transcriptional silencing and genome organization of retrotransposons.

Authors:  David R Lorenz; Irina V Mikheyeva; Peter Johansen; Lauren Meyer; Anastasia Berg; Shiv I S Grewal; Hugh P Cam
Journal:  Mol Cell Biol       Date:  2012-08-20       Impact factor: 4.272

5.  Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L.

Authors:  Déborah Bourc'his; Timothy H Bestor
Journal:  Nature       Date:  2004-08-18       Impact factor: 49.962

6.  Maintenance of genomic methylation requires a SWI2/SNF2-like protein.

Authors:  J A Jeddeloh; T L Stokes; E J Richards
Journal:  Nat Genet       Date:  1999-05       Impact factor: 38.330

7.  Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse.

Authors:  Yuzuru Kato; Masahiro Kaneda; Kenichiro Hata; Kenji Kumaki; Mizue Hisano; Yuji Kohara; Masaki Okano; En Li; Masami Nozaki; Hiroyuki Sasaki
Journal:  Hum Mol Genet       Date:  2007-07-06       Impact factor: 6.150

8.  Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila.

Authors:  Julius Brennecke; Alexei A Aravin; Alexander Stark; Monica Dus; Manolis Kellis; Ravi Sachidanandam; Gregory J Hannon
Journal:  Cell       Date:  2007-03-08       Impact factor: 41.582

9.  Characterization of the structure, function, and mechanism of B2 RNA, an ncRNA repressor of RNA polymerase II transcription.

Authors:  Celso A Espinoza; James A Goodrich; Jennifer F Kugel
Journal:  RNA       Date:  2007-02-16       Impact factor: 4.942

10.  Gene expression and stress response mediated by the epigenetic regulation of a transposable element small RNA.

Authors:  Andrea D McCue; Saivageethi Nuthikattu; Sarah H Reeder; R Keith Slotkin
Journal:  PLoS Genet       Date:  2012-02-09       Impact factor: 5.917

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  16 in total

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Journal:  Plant Physiol       Date:  2014-05-28       Impact factor: 8.340

2.  Expression analysis of argonaute, Dicer-like, and RNA-dependent RNA polymerase genes in cucumber (Cucumis sativus L.) in response to abiotic stress.

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Journal:  J Genet       Date:  2017-06       Impact factor: 1.166

3.  microRNAs and the evolution of complex multicellularity: identification of a large, diverse complement of microRNAs in the brown alga Ectocarpus.

Authors:  James E Tarver; Alexandre Cormier; Natalia Pinzón; Richard S Taylor; Wilfrid Carré; Martina Strittmatter; Hervé Seitz; Susana M Coelho; J Mark Cock
Journal:  Nucleic Acids Res       Date:  2015-06-22       Impact factor: 16.971

4.  Sequence composition of BAC clones and SSR markers mapped to Upland cotton chromosomes 11 and 21 targeting resistance to soil-borne pathogens.

Authors:  Congli Wang; Mauricio Ulloa; Xinyi Shi; Xiaohui Yuan; Christopher Saski; John Z Yu; Philip A Roberts
Journal:  Front Plant Sci       Date:  2015-10-02       Impact factor: 5.753

5.  Gene expression changes in Porphyromonas gingivalis W83 after inoculation in rat oral cavity.

Authors:  Jian Zhao; Qian Li; Chun-Ling Pan; Jun-Chao Liu; Hong-Yan Wang; Li-Si Tan; Ya-Ping Pan
Journal:  BMC Microbiol       Date:  2015-05-24       Impact factor: 3.605

Review 6.  Transposons, environmental changes, and heritable induced phenotypic variability.

Authors:  Lucia Piacentini; Laura Fanti; Valeria Specchia; Maria Pia Bozzetti; Maria Berloco; Gino Palumbo; Sergio Pimpinelli
Journal:  Chromosoma       Date:  2014-04-22       Impact factor: 4.316

7.  Arabidopsis MSH1 mutation alters the epigenome and produces heritable changes in plant growth.

Authors:  Kamaldeep S Virdi; John D Laurie; Ying-Zhi Xu; Jiantao Yu; Mon-Ray Shao; Robersy Sanchez; Hardik Kundariya; Dong Wang; Jean-Jack M Riethoven; Yashitola Wamboldt; Maria P Arrieta-Montiel; Vikas Shedge; Sally A Mackenzie
Journal:  Nat Commun       Date:  2015-02-27       Impact factor: 14.919

Review 8.  Reconsidering plant memory: Intersections between stress recovery, RNA turnover, and epigenetics.

Authors:  Peter A Crisp; Diep Ganguly; Steven R Eichten; Justin O Borevitz; Barry J Pogson
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9.  The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila.

Authors:  Chao-Yin Cheng; Janet M Young; Chih-Yi Gabriela Lin; Ju-Lan Chao; Harmit S Malik; Meng-Chao Yao
Journal:  Genes Dev       Date:  2016-12-15       Impact factor: 11.361

10.  The N-terminus of IFT46 mediates intraflagellar transport of outer arm dynein and its cargo-adaptor ODA16.

Authors:  Yuqing Hou; George B Witman
Journal:  Mol Biol Cell       Date:  2017-07-12       Impact factor: 4.138

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