Literature DB >> 24250962

Pulmonary Complications due to Esophagectomy.

Abulfazl Shirinzadeh1, Yashar Talebi.   

Abstract

INTRODUCTION: Esophageal carcinoma is the scourge of human beings. Pulmonary complications in patients who have undergone operation are common (20-30% of cases) and there are no suitable tools and ways to predict these complications.
METHODS: During a period of 10 years, from March 1998 to February 2007, 200 patients (150 male and 50 female) underwent Esophagectomy due to esophageal carcinoma in thoracic surgery ward retrospectively. Complications include the length of hospitalization, mechanical ventilation, morbidity and mortality. Patients' risk factors include age, preoperative chemo-radiotherapy, stage of the disease and preoperative spirometry condition.
RESULTS: WE GROUPED OUR PATIENTS INTO THREE CATEGORIES: Normal (FEV1 ≥ 80% predicted), mildly impaired (FEV1 65% to 79% predicted), more severely impaired (FEV1 < 65% predicted).Although almost all patients had radiographic pulmonary abnormalities, significant pulmonary complications occurred in 40 patients (20%) which underwent Esophagectomy. Pleural effusion and atelectasia in 160 patients (80%). 24 patients needed chest-tube insertion. 20 patients (10%) developed ARDS. 14 patients (7%) developed chylothorax. 20 patients (10%) of patients died during their postoperative hospital stay. 30 patients (15%) required mechanical ventilation for greater than 48 hours.
CONCLUSION: We reviewed a number of preoperative clinical variables to determine whether they contributed to postoperative pulmonary complications as well as other outcomes. In general, age, impaired pulmonary function especially in those patients with FEV1 less than 65% predicted was associated with prolonged hospital length of stay (LOS). In fact pulmonary complications rate after Esophagectomy are high and there was associated mortality and morbidity.

Entities:  

Keywords:  Esophagectomy; Pulmonary Complication; Pulmonary Resection

Year:  2011        PMID: 24250962      PMCID: PMC3825331          DOI: 10.5681/jcvtr.2011.020

Source DB:  PubMed          Journal:  J Cardiovasc Thorac Res        ISSN: 2008-5117


  20 in total

1.  Relationship between preoperative assessment of organ function and postoperative morbidity in patients with oesophageal cancer.

Authors:  H Kuwano; K Sumiyoshi; K Sonoda; K Kitamura; S Tsutsui; Y Toh; M Kitamura; K Sugimachi
Journal:  Eur J Surg       Date:  1998-08

2.  Thoracic esophageal carcinoma above the carina: a more formidable adversary?

Authors:  H Kato; Y Tachimori; H Watanabe; H Yamaguchi; T Ishikawa; Y Kagami
Journal:  J Surg Oncol       Date:  1997-05       Impact factor: 3.454

3.  Transthoracic versus transhiatal resection for carcinoma of the esophagus: a meta-analysis.

Authors:  J B Hulscher; J G Tijssen; H Obertop; J J van Lanschot
Journal:  Ann Thorac Surg       Date:  2001-07       Impact factor: 4.330

4.  Mortality after esophagectomy: risk factor analysis.

Authors:  M K Ferguson; T R Martin; L B Reeder; J Olak
Journal:  World J Surg       Date:  1997 Jul-Aug       Impact factor: 3.352

5.  Analysis of reduced death and complication rates after esophageal resection.

Authors:  B P Whooley; S Law; S C Murthy; A Alexandrou; J Wong
Journal:  Ann Surg       Date:  2001-03       Impact factor: 12.969

6.  Pulmonary complications after esophagectomy.

Authors:  Christopher E Avendano; Patrick A Flume; Gerard A Silvestri; Lydia B King; Carolyn E Reed
Journal:  Ann Thorac Surg       Date:  2002-03       Impact factor: 4.330

7.  Risk stratification and long-term results after surgical treatment of carcinomas of the thoracic esophagus and cardia. A 25-year retrospective study.

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Journal:  J Thorac Cardiovasc Surg       Date:  1990-02       Impact factor: 5.209

8.  Prediction of pulmonary complications after transthoracic oesophagectomy.

Authors:  H Nagawa; O Kobori; T Muto
Journal:  Br J Surg       Date:  1994-06       Impact factor: 6.939

9.  Risk analysis in resection of squamous cell carcinoma of the esophagus.

Authors:  S Y Law; M Fok; J Wong
Journal:  World J Surg       Date:  1994 May-Jun       Impact factor: 3.352

10.  A 15-year review of esophagectomy for carcinoma of the esophagus and cardia.

Authors:  K W Millikan; J Silverstein; V Hart; K Blair; S Bines; J Roberts; A Doolas
Journal:  Arch Surg       Date:  1995-06
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Journal:  Esophagus       Date:  2022-02-26       Impact factor: 4.230

3.  Prevention of post-operative complications by using a HMG-CoA reductase inhibitor in patients undergoing one-lung ventilation for non-cardiac surgery: study protocol for a randomised controlled trial.

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4.  Evaluation of oesophageal and gastric resection outcomes in a small-volume unit.

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