Literature DB >> 24249533

Are younger patients undergoing TKAs appropriately characterized as active?

James A Keeney1, Ryan M Nunley, Rick W Wright, Robert L Barrack, John C Clohisy.   

Abstract

BACKGROUND: The use of TKAs in young patients is increasing. Demographic characteristics and activity levels among this patient group may affect implant selection, performance, and survivorship. Patient age (≤ 55 years) and preoperative diagnosis have been used to define this patient group, with the presumption that these patients are more active than older patients with similar indications for TKA. QUESTIONS/PURPOSES: We questioned whether (1) demographic features of young patients support high activity expectations after TKA, and (2) preoperative or postoperative functional activity measures support projections that young patients are active after TKA.
METHODS: We retrospectively compared demographic characteristics (gender, BMI, diagnosis) and functional activity profile (as determined by preoperative and postoperative UCLA activity score and functional subscores of The Knee Society and WOMAC instruments) for 150 patients 55 years old or younger (181 TKAs) and 262 patients who were between 65 to 75 years old (314 TKAs) at the time of surgery.
RESULTS: Younger patients having TKAs were significantly more likely than older patients to be female (74% versus 60%, p < 0.001) and to have diagnoses other than osteoarthritis (18% versus 3%, p < 0.001). BMI was significantly greater among younger female patients than among other age and gender combinations (35 kg/m(2) versus 31 kg/m(2), p < 0.001). Male patients had higher mean postoperative UCLA activity scores (5.5 versus 4.4, p < 0.001), Knee Society function subscores (80.2 versus 66.4, p < 0.001), and WOMAC function subscores (82.8 versus 74.2, p < 0.01) compared with female patients, but these were not different in older versus younger patients.
CONCLUSIONS: Sustained high activity levels are not likely to be a principal cause of revision TKAs among younger patients when considering age and diagnosis alone. Determining the effect of activity on survivorship of prosthetic designs and techniques should be based on measured functional activity instead of using age and diagnosis as surrogates for activity. LEVEL OF EVIDENCE: Level III, therapeutic study. See the Instructions for Authors for a complete description of levels of evidence.

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Year:  2013        PMID: 24249533      PMCID: PMC3940741          DOI: 10.1007/s11999-013-3376-x

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  35 in total

1.  The Knee Society total knee arthroplasty roentgenographic evaluation and scoring system.

Authors:  F C Ewald
Journal:  Clin Orthop Relat Res       Date:  1989-11       Impact factor: 4.176

2.  Total knee arthroplasty in young adults who have rheumatoid arthritis.

Authors:  M J Stuart; J A Rand
Journal:  J Bone Joint Surg Am       Date:  1988-01       Impact factor: 5.284

3.  Cementless total knee replacement in patients 50 years old and under.

Authors:  D S Hungerford; K A Krackow; R V Kenna
Journal:  Orthop Clin North Am       Date:  1989-04       Impact factor: 2.472

4.  Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee.

Authors:  N Bellamy; W W Buchanan; C H Goldsmith; J Campbell; L W Stitt
Journal:  J Rheumatol       Date:  1988-12       Impact factor: 4.666

5.  Cemented total knee arthroplasty for gonarthrosis in patients 55 years old or younger.

Authors:  S H Stern; M K Bowen; J N Insall; G R Scuderi
Journal:  Clin Orthop Relat Res       Date:  1990-11       Impact factor: 4.176

6.  Cementless total knee arthroplasty in patients 50 years or younger.

Authors:  Aaron A Hofmann; Scott M Heithoff; Marcelo Camargo
Journal:  Clin Orthop Relat Res       Date:  2002-11       Impact factor: 4.176

7.  Total knee arthroplasty for patients younger than 55 years.

Authors:  C S Ranawat; D E Padgett; Y Ohashi
Journal:  Clin Orthop Relat Res       Date:  1989-11       Impact factor: 4.176

8.  Factors affecting the durability of primary total knee prostheses.

Authors:  James A Rand; Robert T Trousdale; Duane M Ilstrup; W Scott Harmsen
Journal:  J Bone Joint Surg Am       Date:  2003-02       Impact factor: 5.284

9.  Treatment of primary osteoarthritis of the hip. A comparison of total joint and surface replacement arthroplasty.

Authors:  H C Amstutz; B J Thomas; R Jinnah; W Kim; T Grogan; C Yale
Journal:  J Bone Joint Surg Am       Date:  1984-02       Impact factor: 5.284

10.  Higher cumulative revision rate of knee arthroplasties in younger patients with osteoarthritis.

Authors:  Ola L A Harrysson; Otto Robertsson; Jamal F Nayfeh
Journal:  Clin Orthop Relat Res       Date:  2004-04       Impact factor: 4.176

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1.  Early Lessons From a Worldwide, Multicenter, Followup Study of the Recalled Articular Surface Replacement Hip System.

Authors:  Rami Madanat; Daniel K Hussey; Gabrielle S Donahue; Hollis G Potter; Robert Wallace; Charles Bragdon; Orhun Muratoglu; Henrik Malchau
Journal:  Clin Orthop Relat Res       Date:  2015-08-27       Impact factor: 4.176

Review 2.  Larger range of motion and increased return to activity, but higher revision rates following unicompartmental versus total knee arthroplasty in patients under 65: a systematic review.

Authors:  Laura J Kleeblad; Jelle P van der List; Hendrik A Zuiderbaan; Andrew D Pearle
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-11-28       Impact factor: 4.342

3.  Racial Disparities in Above-knee Amputations After TKA: A National Database Study.

Authors:  Jaiben George; Suparna M Navale; Nicholas K Schiltz; Miguel Siccha; Alison K Klika; Carlos A Higuera
Journal:  Clin Orthop Relat Res       Date:  2017-07       Impact factor: 4.176

4.  What Are the All-Cause Survivorship Rates and Functional Outcomes in Patients Younger Than 55 Years Undergoing Primary Knee Arthroplasty? A Systematic Review.

Authors:  Ryan W Paul; Alim Osman; Ari Clements; Fotios P Tjoumakaris; Jess H Lonner; Kevin B Freedman
Journal:  Clin Orthop Relat Res       Date:  2022-03-01       Impact factor: 4.755

5.  Patient activity after TKA depends on patient-specific parameters.

Authors:  Cornelia Lützner; Stephan Kirschner; Jörg Lützner
Journal:  Clin Orthop Relat Res       Date:  2014-07-23       Impact factor: 4.176

6.  Are younger patients undergoing THA appropriately characterized as active?

Authors:  James A Keeney; Ryan M Nunley; Geneva R Baca; John C Clohisy
Journal:  Clin Orthop Relat Res       Date:  2014-09-23       Impact factor: 4.176

7.  Preoperative characteristics of working-age patients undergoing total knee arthroplasty.

Authors:  Tjerk H Hylkema; Martin Stevens; Jan Van Beveren; Paul C Rijk; Hans Peter van Jonbergen; Reinoud W Brouwer; Sjoerd K Bulstra; Sandra Brouwer
Journal:  PLoS One       Date:  2017-08-25       Impact factor: 3.240

8.  Different incidences of knee arthroplasty in the Nordic countries.

Authors:  Mika J NiemeläInen; Keijo T MäKelä; Otto Robertsson; Annette W-Dahl; Ove Furnes; Anne M Fenstad; Alma B Pedersen; Henrik M Schrøder; Heini Huhtala; Antti Eskelinen
Journal:  Acta Orthop       Date:  2017-01-06       Impact factor: 3.717

9.  Resumption of physical activity and sport after knee replacement.

Authors:  Francesco Pisanu; Matteo Andreozzi; Federico Costagli; Gianfilipo Caggiari; Laura Saderi; Giovanni Sotgiu; Andrea Fabio Manunta
Journal:  J Orthop       Date:  2020-01-25

Review 10.  Return to Sports and Physical Activity After Total and Unicondylar Knee Arthroplasty: A Systematic Review and Meta-Analysis.

Authors:  Suzanne Witjes; Vincent Gouttebarge; P Paul F M Kuijer; Rutger C I van Geenen; Rudolf W Poolman; Gino M M J Kerkhoffs
Journal:  Sports Med       Date:  2016-02       Impact factor: 11.136

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