PURPOSE: The objective of this study was to determine the value of high-field magnetic resonance imaging and to clarify the characteristics of each image among three-dimensional gradient echo (3D-GRE), two-dimensional spin echo (2D-SE) and inversion recovery (2D-IR) sequences used as contrast-enhanced T1-weighted images for stereotactic irradiation treatment planning of sellar lesions. MATERIALS AND METHODS: Pulse sequences of 2D-SE and 3D-spoiled gradient recalled acquisition in the steady state (3D-SPGR) using GRE at 1.5 T and 2D-IR and 3D-fast SPGR (3D-FSPGR) at 3 T after injection of contrast material were acquired for 14 small pituitary tumors. As quantitative methods, signal-to-noise ratios (SNR) and contrast-to-noise ratios (CNR) were evaluated using a region-of-interest analysis. RESULTS: There was no significant difference in SNR between 1.5-T SPGR and 3-T FSPGR, while 3-T IR was superior to 1.5-T SE. The 2D-SE and -IR provided significantly better CNR than 3D-GRE between tumor and normal structures. CONCLUSIONS: Three Tesla was found to be superior to 1.5 T in distinguishing tumors from the normal sellar structure. Optimal dose planning will utilize each advantage of imaging; 3D-GRE allows high-resolution acquisition and 2D-SE and -IR can offer better tissue contrast.
PURPOSE: The objective of this study was to determine the value of high-field magnetic resonance imaging and to clarify the characteristics of each image among three-dimensional gradient echo (3D-GRE), two-dimensional spin echo (2D-SE) and inversion recovery (2D-IR) sequences used as contrast-enhanced T1-weighted images for stereotactic irradiation treatment planning of sellar lesions. MATERIALS AND METHODS: Pulse sequences of 2D-SE and 3D-spoiled gradient recalled acquisition in the steady state (3D-SPGR) using GRE at 1.5 T and 2D-IR and 3D-fast SPGR (3D-FSPGR) at 3 T after injection of contrast material were acquired for 14 small pituitary tumors. As quantitative methods, signal-to-noise ratios (SNR) and contrast-to-noise ratios (CNR) were evaluated using a region-of-interest analysis. RESULTS: There was no significant difference in SNR between 1.5-T SPGR and 3-T FSPGR, while 3-T IR was superior to 1.5-T SE. The 2D-SE and -IR provided significantly better CNR than 3D-GRE between tumor and normal structures. CONCLUSIONS: Three Tesla was found to be superior to 1.5 T in distinguishing tumors from the normal sellar structure. Optimal dose planning will utilize each advantage of imaging; 3D-GRE allows high-resolution acquisition and 2D-SE and -IR can offer better tissue contrast.
Authors: David B Stobo; Robert S Lindsay; John M Connell; Laurence Dunn; Kirsten P Forbes Journal: Clin Endocrinol (Oxf) Date: 2011-11 Impact factor: 3.478
Authors: Nicholas Patronas; Nail Bulakbasi; Constantine A Stratakis; Antony Lafferty; Edward H Oldfield; John Doppman; Lynnette K Nieman Journal: J Clin Endocrinol Metab Date: 2003-04 Impact factor: 5.958
Authors: G Scotti; C Y Yu; W P Dillon; D Norman; N Colombo; T H Newton; J De Groot; C B Wilson Journal: AJR Am J Roentgenol Date: 1988-10 Impact factor: 3.959
Authors: Alexandra A J de Rotte; Amy Groenewegen; Dik R Rutgers; Theo Witkamp; Pierre M J Zelissen; F J Anton Meijer; Erik J van Lindert; Ad Hermus; Peter R Luijten; Jeroen Hendrikse Journal: Eur Radiol Date: 2015-05-20 Impact factor: 5.315