BACKGROUND/AIMS: Acute pancreatitis (AP) evades an etiological diagnosis in up to 10 % to 30 % of patients. This group, ie. idiopathic acute pancreatitis (IAP) is prone to a high recurrence (up to 70 %). Endoscopic ultrasound (EUS) is promising, but there is limited data on elucidating the cause of IAP, from India. This observational study was designed to study the role of EUS after the first episode of IAP. METHODS: All patients diagnosed to have first episode of IAP were included in the study and taken up for EUS examination after 6 weeks. Patients with conditions known to predispose or precipitate AP, like alcohol binge, drugs, metabolic or autoimmune conditions, or even a positive family history, were excluded from the study. RESULT: A total of 51 patients were included. EUS positivity was found in 29 (56.9 %) patients. It included common bile duct (CBD) calculus in 5 (9.8 %), CBD sludge in 4 (7.8 %), gallbladder calculus in 2 (3.9 %), gallbladder sludge in 2 (3.9 %), and chronic pancreatitis (CP) in 16 (31.4 %) patients. Fourteen patients had a normal study and eight patients had indeterminate CP. CONCLUSIONS: EUS is safe and has a reasonable diagnostic yield in patients with first episode of IAP. CP and biliary lithiasis are the most frequent positive findings on EUS. EUS should be included in the diagnostic protocol after the first episode of IAP, rather than waiting for recurrent episodes.
BACKGROUND/AIMS: Acute pancreatitis (AP) evades an etiological diagnosis in up to 10 % to 30 % of patients. This group, ie. idiopathic acute pancreatitis (IAP) is prone to a high recurrence (up to 70 %). Endoscopic ultrasound (EUS) is promising, but there is limited data on elucidating the cause of IAP, from India. This observational study was designed to study the role of EUS after the first episode of IAP. METHODS: All patients diagnosed to have first episode of IAP were included in the study and taken up for EUS examination after 6 weeks. Patients with conditions known to predispose or precipitate AP, like alcohol binge, drugs, metabolic or autoimmune conditions, or even a positive family history, were excluded from the study. RESULT: A total of 51 patients were included. EUS positivity was found in 29 (56.9 %) patients. It included common bile duct (CBD) calculus in 5 (9.8 %), CBD sludge in 4 (7.8 %), gallbladder calculus in 2 (3.9 %), gallbladder sludge in 2 (3.9 %), and chronic pancreatitis (CP) in 16 (31.4 %) patients. Fourteen patients had a normal study and eight patients had indeterminate CP. CONCLUSIONS: EUS is safe and has a reasonable diagnostic yield in patients with first episode of IAP. CP and biliary lithiasis are the most frequent positive findings on EUS. EUS should be included in the diagnostic protocol after the first episode of IAP, rather than waiting for recurrent episodes.
Authors: Marc F Catalano; Anand Sahai; Michael Levy; Joseph Romagnuolo; Maurits Wiersema; William Brugge; Martin Freeman; Kenji Yamao; Marcia Canto; Lyndon V Hernandez Journal: Gastrointest Endosc Date: 2009-02-24 Impact factor: 9.427
Authors: M L Freeman; J A DiSario; D B Nelson; M B Fennerty; J G Lee; D J Bjorkman; C S Overby; J Aas; M E Ryan; G S Bochna; M J Shaw; H W Snady; R V Erickson; J P Moore; J P Roel Journal: Gastrointest Endosc Date: 2001-10 Impact factor: 9.427
Authors: W J Coyle; B C Pineau; P R Tarnasky; W L Knapple; L Aabakken; B J Hoffman; J T Cunningham; R H Hawes; P B Cotton Journal: Endoscopy Date: 2002-08 Impact factor: 10.093
Authors: A V Sahai; M Zimmerman; L Aabakken; P R Tarnasky; J T Cunningham; A van Velse; R H Hawes; B J Hoffman Journal: Gastrointest Endosc Date: 1998-07 Impact factor: 9.427
Authors: Alejandra Tepox-Padrón; Rafael Ambrosio Bernal-Mendez; Gilberto Duarte-Medrano; Adriana Fabiola Romano-Munive; Milton Mairena-Valle; Miguel Ángel Ramírez-Luna; Jose Daniel Marroquin-Reyes; Luis Uscanga; Carlos Chan; Ismael Domínguez-Rosado; Jorge Hernandez-Calleros; Mario Pelaez-Luna; Felix Tellez-Avila Journal: BMJ Open Gastroenterol Date: 2021-01
Authors: Devica S Umans; Hester C Timmerhuis; Nora D Hallensleben; Stefan A Bouwense; Marie-Paule Gf Anten; Abha Bhalla; Rina A Bijlsma; Marja A Boermeester; Menno A Brink; Lieke Hol; Marco J Bruno; Wouter L Curvers; Hendrik M van Dullemen; Brechje C van Eijck; G Willemien Erkelens; Paul Fockens; Erwin J M van Geenen; Wouter L Hazen; Chantal V Hoge; Akin Inderson; Liesbeth M Kager; Sjoerd D Kuiken; Lars E Perk; Jan-Werner Poley; Rutger Quispel; Tessa Eh Römkens; Hjalmar C van Santvoort; Adriaan Citl Tan; Annemieke Y Thijssen; Niels G Venneman; Frank P Vleggaar; Annet McJ Voorburg; Roy Lj van Wanrooij; Ben J Witteman; Robert C Verdonk; Marc G Besselink; Jeanin E van Hooft Journal: BMJ Open Date: 2020-08-20 Impact factor: 2.692