Mary Jo Grap1, Cindy L Munro2, Paul A Wetzel3, Jessica M Ketchum4, V Anne Hamilton5, Curtis N Sessler6. 1. Adult Health and Nursing Systems Department, School of Nursing, Virginia Commonwealth University, Box 980567, Richmond, VA 23298-0567, USA. Electronic address: mjgrap@vcu.edu. 2. University of South Florida, Tampa, FL, USA. 3. Department of Biomedical Engineering, School of Engineering, Virginia Commonwealth University, Richmond, VA, USA. 4. Department of Biostatistics, School of Medicine, VCU Center for Rehabilitation Science and Engineering, Virginia Commonwealth University, Richmond, VA, USA. 5. Adult Health and Nursing Systems Department, School of Nursing, Virginia Commonwealth University, Box 980567, Richmond, VA 23298-0567, USA. 6. Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Abstract
OBJECTIVE: To determine the effect of sedation on physiologic responses and comfort before, during and after a noxious stimulus (endotracheal tube suctioning). METHODS: The sample was a subset of a larger, longitudinal descriptive study, blood for endorphins and saliva for alpha-amylase were obtained before and after suctioning. Heart rate (HR), respiration rate (RR), oxygen saturation (SPO2), and arm and leg actigraphy were continuously recorded. RESULTS: 67 subjects from medical and surgical ICUs were primarily deeply (37%) or mildly sedated (54%) prior to suctioning. Alpha-amylase increased post suctioning (p = 0.04); endorphins did not change (p = 0.58). Neither were modified by sedation. There were no changes in HR, RR or SPO2 post suctioning. Arm (p = 0.007) and leg actigraphy (p = 0.057) changed from baseline and depended on sedation level (p = 0.0005). CONCLUSIONS: While a stress marker did increase during suctioning, only the measure of patient arm movement was significantly affected by sedation level.
OBJECTIVE: To determine the effect of sedation on physiologic responses and comfort before, during and after a noxious stimulus (endotracheal tube suctioning). METHODS: The sample was a subset of a larger, longitudinal descriptive study, blood for endorphins and saliva for alpha-amylase were obtained before and after suctioning. Heart rate (HR), respiration rate (RR), oxygen saturation (SPO2), and arm and leg actigraphy were continuously recorded. RESULTS: 67 subjects from medical and surgical ICUs were primarily deeply (37%) or mildly sedated (54%) prior to suctioning. Alpha-amylase increased post suctioning (p = 0.04); endorphins did not change (p = 0.58). Neither were modified by sedation. There were no changes in HR, RR or SPO2 post suctioning. Arm (p = 0.007) and leg actigraphy (p = 0.057) changed from baseline and depended on sedation level (p = 0.0005). CONCLUSIONS: While a stress marker did increase during suctioning, only the measure of patient arm movement was significantly affected by sedation level.
Authors: K A Puntillo; C White; A B Morris; S T Perdue; J Stanik-Hutt; C L Thompson; L R Wild Journal: Am J Crit Care Date: 2001-07 Impact factor: 2.228
Authors: Curtis N Sessler; Mark S Gosnell; Mary Jo Grap; Gretchen M Brophy; Pam V O'Neal; Kimberly A Keane; Eljim P Tesoro; R K Elswick Journal: Am J Respir Crit Care Med Date: 2002-11-15 Impact factor: 21.405
Authors: Kathleen A Puntillo; Ann B Morris; Carol L Thompson; Julie Stanik-Hutt; Cheri A White; Lorie R Wild Journal: Crit Care Med Date: 2004-02 Impact factor: 7.598
Authors: E Wesley Ely; Brenda Truman; Ayumi Shintani; Jason W W Thomason; Arthur P Wheeler; Sharon Gordon; Joseph Francis; Theodore Speroff; Shiva Gautam; Richard Margolin; Curtis N Sessler; Robert S Dittus; Gordon R Bernard Journal: JAMA Date: 2003-06-11 Impact factor: 56.272
Authors: Kristin E Schwab; An Q To; Jennifer Chang; Bonnie Ronish; Dale M Needham; Jennifer L Martin; Biren B Kamdar Journal: J Intensive Care Med Date: 2019-07-22 Impact factor: 2.889