| Literature DB >> 24227984 |
Kailun Jiang1, Seymour Brownstein, Harmanjatinder S Sekhon, Scott A Laurie, Kay Lam, Steven Gilberg, William Britton.
Abstract
Choroidal metastasis is the most common intraocular neoplasm and is associated with significant morbidity. In a small percentage of patients, ocular manifestation may be the initial presentation of a systemic malignancy and can be diagnostically difficult to distinguish from ocular primary malignancies. Herein, we present a case of a never-smoker whose ocular pathology was integral to the diagnosis and management of a lung adenocarcinoma harboring a rare oncogene. Through this case, we have explored important diagnostic and therapeutic considerations of pulmonary metastases to the choroid.Entities:
Keywords: Adenocarcinoma; Choroidal metastasis; Crizotinib; EML4-ALK translocation; Non-small cell lung carcinoma; Targeted therapy
Year: 2013 PMID: 24227984 PMCID: PMC3770219 DOI: 10.1016/j.sjopt.2013.06.011
Source DB: PubMed Journal: Saudi J Ophthalmol ISSN: 1319-4534