Literature DB >> 24217769

Solving the mystery of H7N9 by crystal balls.

Kwok-Yung Yuen1.   

Abstract

How the novel influenza H7N9 virus crossed species barrier from avian to human is intriguing. Extrapolation from previous studies on H5N1 can be misleading as illustrated by crystallographic studies on the H7 hemagglutinin with G226L substitution; crystal structure of the neuraminidase N9 showed that R294K substitution interferes with binding to sialic acid or antiviral drugs and reduces viral fitness.

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Year:  2013        PMID： 24217769      PMCID： PMC3847578          DOI： 10.1038/cr.2013.150

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  4 in total

1.  Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses.

Authors:  Yi Shi; Wei Zhang; Fei Wang; Jianxun Qi; Ying Wu; Hao Song; Feng Gao; Yuhai Bi; Yanfang Zhang; Zheng Fan; Chengfeng Qin; Honglei Sun; Jinhua Liu; Joel Haywood; Wenjun Liu; Weimin Gong; Dayan Wang; Yuelong Shu; Yu Wang; Jinghua Yan; George F Gao
Journal:  Science       Date:  2013-09-05       Impact factor: 47.728

2.  Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome.

Authors:  Yu Chen; Weifeng Liang; Shigui Yang; Nanping Wu; Hainv Gao; Jifang Sheng; Hangping Yao; Jianer Wo; Qiang Fang; Dawei Cui; Yongcheng Li; Xing Yao; Yuntao Zhang; Haibo Wu; Shufa Zheng; Hongyan Diao; Shichang Xia; Yanjun Zhang; Kwok-Hung Chan; Hoi-Wah Tsoi; Jade Lee-Lee Teng; Wenjun Song; Pui Wang; Siu-Ying Lau; Min Zheng; Jasper Fuk-Woo Chan; Kelvin Kai-Wang To; Honglin Chen; Lanjuan Li; Kwok-Yung Yuen
Journal:  Lancet       Date:  2013-04-25       Impact factor: 79.321

3.  Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses.

Authors:  Yan Wu; Yuhai Bi; Christopher J Vavricka; Xiaoman Sun; Yanfang Zhang; Feng Gao; Min Zhao; Haixia Xiao; Chengfeng Qin; Jianhua He; Wenjun Liu; Jinghua Yan; Jianxun Qi; George F Gao
Journal:  Cell Res       Date:  2013-10-29       Impact factor: 25.617

4.  The emergence of influenza A H7N9 in human beings 16 years after influenza A H5N1: a tale of two cities.

Authors:  Kelvin K W To; Jasper F W Chan; Honglin Chen; Lanjuan Li; Kwok-Yung Yuen
Journal:  Lancet Infect Dis       Date:  2013-09       Impact factor: 25.071
  4 in total
  2 in total

1.  Proton Channel Activity of Influenza A Virus Matrix Protein 2 Contributes to Autophagy Arrest.

Authors:  Yizhong Ren; Chufang Li; Liqiang Feng; Weiqi Pan; Liang Li; Qian Wang; Jiashun Li; Na Li; Ling Han; Xuehua Zheng; Xuefeng Niu; Caijun Sun; Ling Chen
Journal:  J Virol       Date:  2015-10-14       Impact factor: 5.103

2.  Predictors for fatal human infections with avian H7N9 influenza, evidence from four epidemic waves in Jiangsu Province, Eastern China, 2013-2016.

Authors:  Wang Ma; Haodi Huang; Jian Chen; Ke Xu; Qigang Dai; Huiyan Yu; Fei Deng; Xian Qi; Shenjiao Wang; Jie Hong; Changjun Bao; Xiang Huo; Minghao Zhou
Journal:  Influenza Other Respir Viruses       Date:  2017-07-26       Impact factor: 4.380
  2 in total

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