Literature DB >> 24211476

Lack of herd immunity against measles in individuals aged <35 years could explain re-emergence of measles in Catalonia (Spain).

Pedro Plans1, Nuria Torner2, Pere Godoy2, Mireia Jané3.   

Abstract

OBJECTIVES: The objective of this study was to assess the association between lack of herd immunity in some population groups and the re-emergence of measles in Catalonia in 2006.
METHODS: Herd immunity was considered established in the different population groups when the prevalence of positive serological results to measles was higher than the herd immunity threshold of 90%. The Chi-square test and the odds ratio were used to assess the association between lack of herd immunity and measles cases in the outbreak of 2006-2007.
RESULTS: Herd immunity was not established against measles in individuals aged 0-14 years and 25-34 years, as the prevalence of positive serological results was <90% in these groups. In the measles outbreak of 2006-2007, 91% of cases occurred in age groups without herd immunity, and only 9% of cases occurred in age groups with herd immunity (p<0.001). The odds ratio for the association between lack of herd immunity and measles cases in the outbreak of 2006-2007 was 104 (p<0.001).
CONCLUSION: Lack of herd immunity in individuals aged<35 years could be one of the factors underlying the re-emergence of measles in Catalonia.
Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.

Keywords:  Herd immunity; Measles elimination; Measles outbreaks; Prevention; Seroepidemiology

Mesh:

Substances:

Year:  2013        PMID: 24211476     DOI: 10.1016/j.ijid.2013.09.015

Source DB:  PubMed          Journal:  Int J Infect Dis        ISSN: 1201-9712            Impact factor:   3.623


  7 in total

1.  Prevalence of anti-rubella, anti-measles and anti-mumps IgG antibodies in neonates and pregnant women in Catalonia (Spain) in 2013: susceptibility to measles increased from 2003 to 2013.

Authors:  P Plans; F de Ory; M Campins; E Álvarez; T Payà; E Guisasola; C Compte; K Vellbé; C Sánchez; M J Lozano; I Aran; A Bonmatí; R Carreras; M Jané; L Cabero
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2015-02-10       Impact factor: 3.267

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  7 in total

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