Literature DB >> 24201229

Multiple prescribers in older frequent opioid users--does it mean abuse?

C Ineke Neutel, Svetlana Skurtveit, Christian Berg, Solveig Sakshaug.   

Abstract

BACKGROUND: Obtaining analgesic narcotics from multiple prescribers is sometimes called 'doctor-shopping,' implying abuse. If the use of multiple prescribers can be used as an indicator for abuse, it would be a convenient way to study abuse in large populations.
OBJECTIVE: To assess multiple prescribers as an indicator of abuse by relating quantity of opioids obtained by older Norwegians to number of prescribers.
METHODS: Data were obtained from the Norwegian Prescription database which includes all prescriptions filled in Norwegian pharmacies. The study population consisted of people aged 70-89 who filled five or more prescriptions for weak or for strong opioids in 2008.
RESULTS: In 2008, 4,268 persons filled five or more prescriptions for strong opioids and 19,675 for weak opioids. More than 30% had three or more prescribers. Over half of strong opioids users and 72% of weak opioid users had medication-use-periods of over 40 weeks. For strong opioids, increasing DDDs/week was found with increasing number of prescribers. When cancer/palliative care patients were excluded, the mean DDDs/week level for strong opioids was much lower, and little association with number of prescribers remained. For weak opioids, little association between mean DDDs/week and number of prescribers was found.
CONCLUSIONS: This study demonstrated that the increasing quantities of strong opioids with increasing number of prescribers are largely due to treatment of cancer/palliative care patients. While the use of multiple prescribers can be a red flag for problematic medication use, it cannot be considered synonymous with 'doctor-shopping' or abuse.

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Year:  2013        PMID: 24201229

Source DB:  PubMed          Journal:  J Popul Ther Clin Pharmacol        ISSN: 2561-8741


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1.  Exploring the latent trait of opioid use disorder criteria among frequent nonmedical prescription opioid users.

Authors:  João Mauricio Castaldelli-Maia; Laura H Andrade; Katherine M Keyes; Magdalena Cerdá; Daniel J Pilowsky; Silvia S Martins
Journal:  J Psychiatr Res       Date:  2016-05-24       Impact factor: 4.791

Review 2.  A Systematic Review of Opioid and Benzodiazepine Misuse in Older Adults.

Authors:  Rachel D Maree; Zachary A Marcum; Ester Saghafi; Debra K Weiner; Jordan F Karp
Journal:  Am J Geriatr Psychiatry       Date:  2016-06-07       Impact factor: 4.105

3.  Dispensing of benzodiazepines and benzodiazepine-related drugs to pregnant women: a population-based cohort study.

Authors:  Brit Solvor Riska; Svetlana Skurtveit; Kari Furu; Anders Engeland; Marte Handal
Journal:  Eur J Clin Pharmacol       Date:  2014-09-11       Impact factor: 2.953

4.  New means, new measures: assessing prescription drug-seeking indicators over 10 years of the opioid epidemic.

Authors:  Brea L Perry; Meltem Odabaş; Kai-Cheng Yang; Byungkyu Lee; Patrick Kaminski; Brian Aronson; Yong-Yeol Ahn; Carrie B Oser; Patricia R Freeman; Jeffrey C Talbert
Journal:  Addiction       Date:  2021-07-27       Impact factor: 6.526

Review 5.  Early Detection of Prescription Drug Abuse Using Doctor Shopping Monitoring From Claims Databases: Illustration From the Experience of the French Addictovigilance Network.

Authors:  Thomas Soeiro; Clémence Lacroix; Vincent Pradel; Maryse Lapeyre-Mestre; Joëlle Micallef
Journal:  Front Psychiatry       Date:  2021-05-17       Impact factor: 4.157

  5 in total

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