Literature DB >> 24198479

Computer simulation of a novel pharmaceutical silicon nanocarrier.

Saeed Soltani1, Soroush Sardari, Sima Azadi Soror.   

Abstract

We show the potential of the nanosilicon structure of the frustules of a typical diatom, Cymatopleura sp., as a new vehicle for drugs. The basic diatom nanostructure is a lattice of SiO2, and computerized methods in a dock project have identified the most likely and the best drug types to load into such a structure.

Entities:  

Keywords:  artificial neural network; computerized ethods; diatom; docking; simulation

Year:  2010        PMID： 24198479      PMCID： PMC3781697          DOI： 10.2147/NSA.S8378

Source DB:  PubMed          Journal:  Nanotechnol Sci Appl        ISSN： 1177-8903


  8 in total

1.  Effects of physicochemical properties and other factors on systemic nasal drug delivery.

Authors: 
Journal:  Adv Drug Deliv Rev       Date:  1998-01-05       Impact factor: 15.470

2.  Architecture and material properties of diatom shells provide effective mechanical protection.

Authors:  Christian E Hamm; Rudolf Merkel; Olaf Springer; Piotr Jurkojc; Christian Maier; Kathrin Prechtel; Victor Smetacek
Journal:  Nature       Date:  2003-02-20       Impact factor: 49.962

Review 3.  Prediction of physicochemical properties based on neural network modelling.

Authors:  Jyrki Taskinen; Jouko Yliruusi
Journal:  Adv Drug Deliv Rev       Date:  2003-09-12       Impact factor: 15.470

4.  Physicochemical properties of drugs that control absorption rate after subcutaneous implantation.

Authors:  B E BALLARD; E NELSON
Journal:  J Pharmacol Exp Ther       Date:  1962-01       Impact factor: 4.030

Review 5.  Engineering and medical applications of diatoms.

Authors:  Kit Mun Wee; Tony N Rogers; Burhanettin S Altan; Stephen A Hackney; Christian Hamm
Journal:  J Nanosci Nanotechnol       Date:  2005-01

6.  Effect of drug physicochemical properties on in vitro characteristics of amphiphilic cyclodextrin nanospheres and nanocapsules.

Authors:  Erem Memisoglu-Bilensoy; Murat Sen; Atilla A Hincal
Journal:  J Microencapsul       Date:  2006-02       Impact factor: 3.142

7.  Historical processes constrain patterns in global diatom diversity.

Authors:  Wim Vyverman; Elie Verleyen; Koen Sabbe; Koenraad Vanhoutte; Mieke Sterken; Dominic A Hodgson; David G Mann; Steve Juggins; Bart Van de Vijver; Vivienne Jones; Roger Flower; Donna Roberts; Victor A Chepurnov; Cathy Kilroy; Pieter Vanormelingen; Aaike De Wever
Journal:  Ecology       Date:  2007-08       Impact factor: 5.499

8.  Survey of the chemical defence potential of diatoms: screening of fifty one species for alpha,beta,gamma,delta-unsaturated aldehydes.

Authors:  Thomas Wichard; Serge A Poulet; Claudia Halsband-Lenk; Aitor Albaina; Roger Harris; Dongyan Liu; Georg Pohnert
Journal:  J Chem Ecol       Date:  2005-04       Impact factor: 2.626
  8 in total
  2 in total

1.  Prediction of Drug Loading in the Gelatin Matrix Using Computational Methods.

Authors:  Rania M Hathout; AbdelKader A Metwally; Timothy J Woodman; John G Hardy
Journal:  ACS Omega       Date:  2020-01-13

Review 2.  Mechanistic Understanding From Molecular Dynamics Simulation in Pharmaceutical Research 1: Drug Delivery.

Authors:  Alex Bunker; Tomasz Róg
Journal:  Front Mol Biosci       Date:  2020-11-25
  2 in total

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