Literature DB >> 2419560

Synthesis of a new chemically and metabolically stable prostacyclin analogue with high and long-lasting oral activity.

W Skuballa, E Schillinger, C S Stürzebecher, H Vorbrüggen.   

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Year:  1986        PMID： 2419560     DOI： 10.1021/jm00153a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  11 in total

1.  Microsomal prostaglandin e2 synthase-1 modulates the response to vascular injury.

Authors:  Miao Wang; Kaori Ihida-Stansbury; Devashish Kothapalli; Mathieu C Tamby; Zhou Yu; Lihong Chen; Gregory Grant; Yan Cheng; John A Lawson; Richard K Assoian; Peter L Jones; Garret A Fitzgerald
Journal:  Circulation       Date:  2011-01-31       Impact factor: 29.690

2.  The prostacyclin analogue cicaprost inhibits metastasis of tumours of R 3327 MAT Lu prostate carcinoma and SMT 2A mammary carcinoma.

Authors:  M Schirner; M R Schneider
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

3.  Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function.

Authors:  Yan Cheng; Miao Wang; Ying Yu; John Lawson; Colin D Funk; Garret A Fitzgerald
Journal:  J Clin Invest       Date:  2006-04-13       Impact factor: 14.808

4.  The octadecanoic pathway: signal molecules for the regulation of secondary pathways.

Authors:  S Blechert; W Brodschelm; S Hölder; L Kammerer; T M Kutchan; M J Mueller; Z Q Xia; M H Zenk
Journal:  Proc Natl Acad Sci U S A       Date:  1995-05-09       Impact factor: 11.205

5.  Effects of paracetamol and aspirin on neural activity of joint mechanonociceptors in adjuvant arthritis.

Authors:  D S McQueen; A Iggo; G J Birrell; B D Grubb
Journal:  Br J Pharmacol       Date:  1991-09       Impact factor: 8.739

6.  Cicaprost, an orally active prostacyclin analogue: its effects on platelet aggregation and skin blood flow in normal volunteers.

Authors:  J J Belch; M McLaren; C S Lau; I R Mackay; A Bancroft; J McEwen; J M Thompson
Journal:  Br J Clin Pharmacol       Date:  1993-06       Impact factor: 4.335

Review 7.  Antimetastatic action of the prostacyclin analogue cicaprost in experimental mammary tumors.

Authors:  M R Schneider; M Schirner; R B Lichtner; H Graf
Journal:  Breast Cancer Res Treat       Date:  1996       Impact factor: 4.872

8.  The stable prostacyclin analogue Cicaprost inhibits metastasis to lungs and lymph nodes in the 13762NF MTLn3 rat mammary carcinoma.

Authors:  M Schirner; R B Lichtner; M R Schneider
Journal:  Clin Exp Metastasis       Date:  1994-01       Impact factor: 5.150

9.  Stability of prostacyclin analogues: an unusual lack of reactivity in acid-catalyzed alkene hydration.

Authors:  A Magill; C O'Yang; M F Powell
Journal:  Pharm Res       Date:  1988-04       Impact factor: 4.200

10.  Synthesis of novel IP agonists via N-aminoethyl cyclic amines prepared by decarboxylative ring-opening reactions.

Authors:  Yasuhiro Morita; Takeshi Ishigaki; Kuniaki Kawamura; Ryoji Hayashi; Masafumi Isogaya; Mika Kitsukawa; Mitsuko Miyamoto; Masashi Uchida; Katsuhiko Iseki
Journal:  Molecules       Date:  2012-01-31       Impact factor: 4.411
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