Literature DB >> 24195053

New options for uveitis treatment.

Yu He1, Song-Bai Jia, Wei Zhang, Jing-Ming Shi.   

Abstract

Uveitis is one of the most important causes of blindness worldwide. Its etiology and pathogenesis are complicated and have not been well understood. The treatment for uveitis is predominantly based on steroids and immunosuppressants. However, systemic side effects limit their clinical application. With the advancement of molecular biology, some intravitreal implants and biologic agents have been used for the treatment of uveitis. Additionally, novel techniques such as gene therapy and RNA interference are being studied for using as uveitis therapy. This paper reviews recent advances in uveitis treatment.

Entities:  

Keywords:  RNA interference; biologic agents; gene therapy; intravitreal implants; uveitis

Year:  2013        PMID: 24195053      PMCID: PMC3808925          DOI: 10.3980/j.issn.2222-3959.2013.05.29

Source DB:  PubMed          Journal:  Int J Ophthalmol        ISSN: 2222-3959            Impact factor:   1.779


  55 in total

Review 1.  Strategies for silencing human disease using RNA interference.

Authors:  Daniel H Kim; John J Rossi
Journal:  Nat Rev Genet       Date:  2007-03       Impact factor: 53.242

Review 2.  Gene therapy for noninfectious uveitis.

Authors:  C J Chu; S E Barker; A D Dick; R R Ali
Journal:  Ocul Immunol Inflamm       Date:  2012-11-19       Impact factor: 3.070

3.  Efficacy of combination therapy of anti-TNF-α antibody infliximab and methotrexate in refractory entero-Behçet's disease.

Authors:  Shigeru Iwata; Kazuyoshi Saito; Kunihiro Yamaoka; Shizuyo Tsujimura; Masao Nawata; Kentaro Hanami; Yoshiya Tanaka
Journal:  Mod Rheumatol       Date:  2010-11-05       Impact factor: 3.023

4.  Republished review: Gene therapy for ocular diseases.

Authors:  Melissa M Liu; Jingsheng Tuo; Chi-Chao Chan
Journal:  Postgrad Med J       Date:  2011-07       Impact factor: 2.401

5.  A comparison between the fluocinolone acetonide (Retisert) and dexamethasone (Ozurdex) intravitreal implants in uveitis.

Authors:  Cheryl A Arcinue; Olga M Cerón; C Stephen Foster
Journal:  J Ocul Pharmacol Ther       Date:  2013-01-08       Impact factor: 2.671

Review 6.  Understanding uveitis: the impact of research on visual outcomes.

Authors:  Marc D de Smet; Simon R J Taylor; Bahram Bodaghi; Elisabetta Miserocchi; Philip I Murray; Uwe Pleyer; Manfred Zierhut; Talin Barisani-Asenbauer; Phuc LeHoang; Sue Lightman
Journal:  Prog Retin Eye Res       Date:  2011-07-22       Impact factor: 21.198

7.  Treatment of refractory uveitis with adalimumab: a prospective multicenter study of 131 patients.

Authors:  Manuel Díaz-Llopis; David Salom; Carmen Garcia-de-Vicuña; Miguel Cordero-Coma; Gabriela Ortega; Norberto Ortego; Marta Suarez-de-Figueroa; Maria J Rio-Pardo; Carlos Fernandez-Cid; Alex Fonollosa; Ricardo Blanco; Angel M Garcia-Aparicio; Jose M Benitez-Del-Castillo; Jose L Olea; J Fernando Arevalo
Journal:  Ophthalmology       Date:  2012-04-21       Impact factor: 12.079

8.  Treatment of retinal vasculitis in Behçet's disease with rituximab.

Authors:  Shahram Sadreddini; Hamid Noshad; Mahshid Molaeefard; Rahim Noshad
Journal:  Mod Rheumatol       Date:  2008-04-26       Impact factor: 3.023

9.  Down-regulation of inducible co-stimulator (ICOS) by intravitreal injection of small interfering RNA (siRNA) plasmid suppresses ongoing experimental autoimmune uveoretinitis in rats.

Authors:  Yongsheng Hou; Lin Xing; Shaoying Fu; Xiaoning Zhang; Jingjing Liu; Hongling Liu; Bingjie Lv; Hao Cui
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2009-01-06       Impact factor: 3.117

10.  Adalimumab successful in sarcoidosis patients with refractory chronic non-infectious uveitis.

Authors:  R J Erckens; R L M Mostard; P A H M Wijnen; J S Schouten; M Drent
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2011-11-27       Impact factor: 3.117

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  4 in total

1.  Efficacy of systemic diclofenac sodium on intravitreal concentration.

Authors:  Yunes Panahi; Mostafa Naderi; Khosrow Jadidi; Hadise Hoseini; Mojtaba Abrishami
Journal:  Int Ophthalmol       Date:  2017-01-10       Impact factor: 2.031

2.  Imbalance Between Th17 Cells and Regulatory T Cells During Monophasic Experimental Autoimmune Uveitis.

Authors:  Lian Zhang; Fangzhu Wan; Jike Song; Kai Tang; Fengming Zheng; Junguo Guo; Dadong Guo; Hongsheng Bi
Journal:  Inflammation       Date:  2016-02       Impact factor: 4.092

3.  Superoxide Dismutase 1 Nanozyme for Treatment of Eye Inflammation.

Authors:  Olga A Kost; Olga V Beznos; Nina G Davydova; Devika S Manickam; Irina I Nikolskaya; Anna E Guller; Petr V Binevski; Natalia B Chesnokova; Anatoly B Shekhter; Natalia L Klyachko; Alexander V Kabanov
Journal:  Oxid Med Cell Longev       Date:  2015-12-01       Impact factor: 6.543

Review 4.  Pharmacotherapy for uveitis: current management and emerging therapy.

Authors:  Robert J Barry; Quan Dong Nguyen; Richard W Lee; Philip I Murray; Alastair K Denniston
Journal:  Clin Ophthalmol       Date:  2014-09-22
  4 in total

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