Literature DB >> 24194429

Antigen-induced eosinophil chemotactic factor (ECF) release by human leukocytes.

B M Czarnetzki1, W König, L M Lichtenstein.   

Abstract

A complement-independent eosinophil chemotactic factor (ECF) is described which is released from peripheral leukocytes of allergic and normal human volunteers after antigen stimulation and after exposure to anti-IgE. Dose response and time-release curves for ECF and histamine run closely parallel in this system. Histamine by itself is shown to have no effect on chemotaxis at the concentrations present in antigen-induced release, but is inhibitory at very high concentrations. Evidence suggests that the ECF released from human leukocytes is derived from basophils and is similar, or identical, to the ECF released from mast cells.

Entities:  

Year:  1976        PMID： 24194429     DOI： 10.1007/BF00917530

Source DB:  PubMed          Journal:  Inflammation        ISSN： 0360-3997            Impact factor:   4.092


  36 in total

1.  Studies in experimental eosinophilia. I. Repeated quantitation of peritoneal eosinophilia in guinea pigs by a method of peritoneal lavage.

Authors:  M LITT
Journal:  Blood       Date:  1960-09       Impact factor: 22.113

2.  Eosinophils and immune mechanisms. II. Partial characterization of the lymphokine eosinophil stimulation promoter.

Authors:  B M Greene; D G Colley
Journal:  J Immunol       Date:  1974-09       Impact factor: 5.422

3.  Chemotaxis of human eosinophils.

Authors:  P A Ward
Journal:  Am J Pathol       Date:  1969-01       Impact factor: 4.307

4.  The IgE-mediated release of an eosinophil leukocyte chemotactic factor from human lung.

Authors:  A B Kay; K F Austen
Journal:  J Immunol       Date:  1971-09       Impact factor: 5.422

5.  Partial characterization of the protein components of eosinophil granules isolated from guinea pig exudates.

Authors:  T P Gessner; R Himmelhoch; E Shelton
Journal:  Arch Biochem Biophys       Date:  1973-06       Impact factor: 4.013

6.  Eosinophil cell separation from human peripheral blood.

Authors:  R P Day
Journal:  Immunology       Date:  1970-06       Impact factor: 7.397

7.  The accumulation of eosinophils as an allergic response to allergen applied to the denuded skin surface.

Authors:  J W Fowler; V C Lowell
Journal:  J Allergy       Date:  1966-01

8.  Mechanisms of passive sensitization. I. Presence of IgE and IgG molecules on human leukocytes.

Authors:  K Ishizaka; H Tomioka; T Ishizaka
Journal:  J Immunol       Date:  1970-12       Impact factor: 5.422

9.  The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes.

Authors:  S BOYDEN
Journal:  J Exp Med       Date:  1962-03-01       Impact factor: 14.307

10.  Identification of a major basic protein in guinea pig eosinophil granules.

Authors:  G J Gleich; D A Loegering; J E Maldonado
Journal:  J Exp Med       Date:  1973-06-01       Impact factor: 14.307
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  2 in total

1.  Mast cell-mediated reactions of host defense and tissue injury: the regulatory role of eosinophil polymorphonuclear leukocytes.

Authors:  E J Goetzl
Journal:  Inflammation       Date:  1977-09       Impact factor: 4.092

2.  Chemotactic efficiency of various chemoattractants for polymorphonuclear leukocytes in inflammatory acne vulgaris.

Authors:  J Knop; T Bossecker; P M Kövary
Journal:  Arch Dermatol Res       Date:  1982       Impact factor: 3.017
  2 in total

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