Literature DB >> 24190503

Test systems of developmental toxicity: state-of-the art and future perspectives.

Marcel Leist1, Annette Ringwald, Raivo Kolde, Susanne Bremer, Christoph van Thriel, Karl-Heinz Krause, Jörg Rahnenführer, Agapios Sachinidis, Jürgen Hescheler, Jan G Hengstler.   

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Year:  2013        PMID： 24190503     DOI： 10.1007/s00204-013-1154-x

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


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  11 in total

Review 1.  Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities.

Authors:  Lena Smirnova; Helena T Hogberg; Marcel Leist; Thomas Hartung
Journal:  ALTEX       Date:  2014       Impact factor: 6.043

2.  Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation.

Authors:  Vaibhav Shinde; Stefanie Klima; Perumal Srinivasan Sureshkumar; Kesavan Meganathan; Smita Jagtap; Eugen Rempel; Jörg Rahnenführer; Jan Georg Hengstler; Tanja Waldmann; Jürgen Hescheler; Marcel Leist; Agapios Sachinidis
Journal:  J Vis Exp       Date:  2015-06-17       Impact factor: 1.355

3.  International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes.

Authors:  Anna Bal-Price; Kevin M Crofton; Marcel Leist; Sandra Allen; Michael Arand; Timo Buetler; Nathalie Delrue; Rex E FitzGerald; Thomas Hartung; Tuula Heinonen; Helena Hogberg; Susanne Hougaard Bennekou; Walter Lichtensteiger; Daniela Oggier; Martin Paparella; Marta Axelstad; Aldert Piersma; Eva Rached; Benoît Schilter; Gabriele Schmuck; Luc Stoppini; Enrico Tongiorgi; Manuela Tiramani; Florianne Monnet-Tschudi; Martin F Wilks; Timo Ylikomi; Ellen Fritsche
Journal:  Arch Toxicol       Date:  2015-01-25       Impact factor: 5.153

4.  Expression classifiers for developmental toxicants.

Authors:  Raymond Reif
Journal:  EXCLI J       Date:  2015-12-22       Impact factor: 4.068

5.  Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay.

Authors:  Marilena Colaianna; Sten Ilmjärv; Hedi Peterson; Ilse Kern; Stephanie Julien; Mathurin Baquié; Giorgia Pallocca; Sieto Bosgra; Agapios Sachinidis; Jan G Hengstler; Marcel Leist; Karl-Heinz Krause
Journal:  Arch Toxicol       Date:  2016-03-25       Impact factor: 5.153

6.  Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells.

Authors:  Vaibhav Shinde; Sureshkumar Perumal Srinivasan; Margit Henry; Tamara Rotshteyn; Jürgen Hescheler; Jörg Rahnenführer; Marianna Grinberg; Johannes Meisig; Nils Blüthgen; Tanja Waldmann; Marcel Leist; Jan Georg Hengstler; Agapios Sachinidis
Journal:  Stem Cell Res Ther       Date:  2016-12-30       Impact factor: 6.832

7.  Transcriptome based differentiation of harmless, teratogenetic and cytotoxic concentration ranges of valproic acid.

Authors:  Regina Stöber
Journal:  EXCLI J       Date:  2014-12-11       Impact factor: 4.068

8.  Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery.

Authors:  B Zimmer; G Pallocca; N Dreser; S Foerster; T Waldmann; J Westerhout; S Julien; K H Krause; C van Thriel; J G Hengstler; A Sachinidis; S Bosgra; M Leist
Journal:  Arch Toxicol       Date:  2014-04-02       Impact factor: 5.153

9.  Biomarker: the universe of chemically induced gene expression alterations in human hepatocyte.

Authors:  Seddik Hammad; Hassan Ahmed
Journal:  EXCLI J       Date:  2014-12-09       Impact factor: 4.068

10.  Transcriptomics in developmental toxicity testing.

Authors:  H M Bolt
Journal:  EXCLI J       Date:  2013-12-12       Impact factor: 4.068
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