Literature DB >> 24189291

The nature and evolution of insight in schizophrenia: a multi-informant longitudinal study of first-episode versus chronic patients.

Danny Koren1, Polina Viksman, Anthony J Giuliano, Larry J Seidman.   

Abstract

BACKGROUND AND AIMS: This study investigated a novel distinction between two possible sources of poor insight in schizophrenia: primary unawareness, in which the ill person is not aware that other people think one has a problem, and secondary unawareness (or disagreement), in which a person does appreciate that other people think one has a problem. A secondary goal was to compare the evolution of insight in first-episode and chronic schizophrenia.
METHODS: Sixty-eight first-episode and 51 chronic patients were administered two versions of the Scale of Unawareness of Mental Disorder (SUMD) at three time points: hospital admission, discharge, and 6-month post-discharge. In the first standard SUMD version, they were asked about their own opinions, whereas in the second modified version, they were asked about their best guess of their doctor's opinion.
RESULTS: While overall level of unawareness remained stable within each single episode, there were significant Type of Unawareness (primary versus secondary) by Clinical Status (admission versus discharge versus 6-month post-discharge) and Type of Unawareness by Phase of Illness (first-episode versus chronic) interaction effects. More specifically, in the first-episode group, primary unawareness steadily decreased over time. In contrast, in the chronic group, primary unawareness decreased markedly during hospitalization and returned to baseline after discharge.
CONCLUSIONS: These results provide preliminary support for the notion that impaired insight is an additive outcome of primary unawareness and disagreement, and that change in insight over time occurs mostly at the level of their relative proportion as opposed to their overall sum. Implications for studying and treating poor insight in schizophrenia are discussed.
© 2013 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  First-episode; Insight; Schizophrenia; Unawareness

Mesh:

Substances:

Year:  2013        PMID: 24189291     DOI: 10.1016/j.schres.2013.10.013

Source DB:  PubMed          Journal:  Schizophr Res        ISSN: 0920-9964            Impact factor:   4.939


  8 in total

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Journal:  Int J Methods Psychiatr Res       Date:  2018-05-22       Impact factor: 4.035

Review 2.  The effects of aging on insight into illness in schizophrenia: a review.

Authors:  Philip Gerretsen; Eric Plitman; Tarek K Rajji; Ariel Graff-Guerrero
Journal:  Int J Geriatr Psychiatry       Date:  2014-07-23       Impact factor: 3.485

3.  Metacognitive Deficits Predict Impaired Insight in Schizophrenia Across Symptom Profiles: A Latent Class Analysis.

Authors:  Paul H Lysaker; Emily Gagen; Abigail Wright; Jenifer L Vohs; Marina Kukla; Phillip T Yanos; Ilanit Hasson-Ohayon
Journal:  Schizophr Bull       Date:  2019-01-01       Impact factor: 9.306

4.  Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments.

Authors:  Paul H Lysaker; Michelle L Pattison; Bethany L Leonhardt; Scott Phelps; Jenifer L Vohs
Journal:  World Psychiatry       Date:  2018-02       Impact factor: 49.548

5.  The "Insight Paradox" in Schizophrenia: Magnitude, Moderators and Mediators of the Association Between Insight and Depression.

Authors:  Martino Belvederi Murri; Mario Amore; Pietro Calcagno; Matteo Respino; Valentina Marozzi; Mattia Masotti; Michele Bugliani; Marco Innamorati; Maurizio Pompili; Silvana Galderisi; Mario Maj
Journal:  Schizophr Bull       Date:  2016-04-11       Impact factor: 9.306

6.  Intact implicit processing of facial threat cues in schizophrenia.

Authors:  Jonathon R Shasteen; Amy E Pinkham; Skylar Kelsven; Kelsey Ludwig; B Keith Payne; David L Penn
Journal:  Schizophr Res       Date:  2015-12-08       Impact factor: 4.939

7.  Accuracy of self-assessment of real-life functioning in schizophrenia.

Authors:  Paola Rocca; Claudio Brasso; Cristiana Montemagni; Silvio Bellino; Alessandro Rossi; Alessandro Bertolino; Dino Gibertoni; Eugenio Aguglia; Mario Amore; Ileana Andriola; Antonello Bellomo; Paola Bucci; Antonino Buzzanca; Bernardo Carpiniello; Alessandro Cuomo; Liliana Dell'Osso; Angela Favaro; Giulia Maria Giordano; Carlo Marchesi; Palmiero Monteleone; Lucio Oldani; Maurizio Pompili; Rita Roncone; Rodolfo Rossi; Alberto Siracusano; Antonio Vita; Patrizia Zeppegno; Silvana Galderisi; Mario Maj
Journal:  NPJ Schizophr       Date:  2021-02-15

8.  Lessons learnt? The importance of metacognition and its implications for Cognitive Remediation in schizophrenia.

Authors:  Matteo Cella; Clare Reeder; Til Wykes
Journal:  Front Psychol       Date:  2015-09-01
  8 in total

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