Fernando Zegers-Hochschild1, Ragaa Mansour2, Osamu Ishihara3, G David Adamson4, Jacques de Mouzon5, Karl G Nygren6, Elizabeth A Sullivan7. 1. Clinica las Condes and Program of Ethics and Public Policies In Human Reproduction, University Diego Portales, Santiago, Chile. Electronic address: fzegers@clc.cl. 2. Egyptian IVF-ET Center, Cairo, Egypt. 3. Saitama Medical University Hospital, Moroyama, Japan. 4. Palo Alto Medical Foundation Fertility Physicians of Northern California, Palo Alto and San Jose, California. 5. IVF Unit, Institut National de la Santé et de la Recherche Médicale Service de Gynécologie Obstétrique II et de Médecine de la Reproduction, Groupe Hospitalier Cochin-Saint Vincet de Paul, Paris, France. 6. Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. 7. National Perinatal Epidemiology and Statistics Unit, School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia.
Abstract
OBJECTIVE: To analyze information on assisted reproductive technology (ART) performed worldwide and trends in outcomes over successive years. DESIGN: Cross-sectional survey on access, effectiveness, and safety of ART procedures performed in 53 countries during 2005. SETTING: A total of 2,973 clinics from national and regional ART registries. PATIENT(S): Infertile women and men undergoing ART globally. INTERVENTION(S): Collection and analysis of international ART data. MAIN OUTCOME MEASURE(S): Number of cycles performed by country and region, including pregnancies, single and multiple birth rates, and perinatal mortality. RESULT(S): Overall, 1,052,363 ART procedures resulted in an estimated 237,315 babies born. The availability of ART varied by country from 15 to 3,982 cycles per million of population. Of all initiated fresh cycles, 62.9% were intracytoplasmic sperm injection. The overall delivery rate per fresh aspiration was 19.6% and for frozen embryo transfer 17.4%, with a cumulative delivery rate of 23.9%. With wide regional variations, single embryo transfer represented 17.5% of cycles, and the proportion of deliveries with twins and triplets from fresh transfers was 23.6% and 1.5%, respectively. CONCLUSION(S): Systematic collection and dissemination of international ART data allows patients, health professionals, and policy makers to examine and compare the impact of reproductive strategies or lack of them as markers of reproductive health.
OBJECTIVE: To analyze information on assisted reproductive technology (ART) performed worldwide and trends in outcomes over successive years. DESIGN: Cross-sectional survey on access, effectiveness, and safety of ART procedures performed in 53 countries during 2005. SETTING: A total of 2,973 clinics from national and regional ART registries. PATIENT(S): Infertile women and men undergoing ART globally. INTERVENTION(S): Collection and analysis of international ART data. MAIN OUTCOME MEASURE(S): Number of cycles performed by country and region, including pregnancies, single and multiple birth rates, and perinatal mortality. RESULT(S): Overall, 1,052,363 ART procedures resulted in an estimated 237,315 babies born. The availability of ART varied by country from 15 to 3,982 cycles per million of population. Of all initiated fresh cycles, 62.9% were intracytoplasmic sperm injection. The overall delivery rate per fresh aspiration was 19.6% and for frozen embryo transfer 17.4%, with a cumulative delivery rate of 23.9%. With wide regional variations, single embryo transfer represented 17.5% of cycles, and the proportion of deliveries with twins and triplets from fresh transfers was 23.6% and 1.5%, respectively. CONCLUSION(S): Systematic collection and dissemination of international ART data allows patients, health professionals, and policy makers to examine and compare the impact of reproductive strategies or lack of them as markers of reproductive health.
Authors: Lidia Mínguez-Alarcón; Paige L Williams; Irene Souter; Caitlin Sacha; Chitra J Amarasiriwardena; Jennifer B Ford; Russ Hauser; Jorge E Chavarro Journal: Int J Hyg Environ Health Date: 2021-08-10 Impact factor: 7.401
Authors: Carmen Messerlian; Vicente Mustieles; Lidia Minguez-Alarcon; Jennifer B Ford; Antonia M Calafat; Irene Souter; Paige L Williams; Russ Hauser Journal: Environ Int Date: 2018-02-22 Impact factor: 9.621
Authors: Carmen Messerlian; Paige L Williams; Jennifer B Ford; Jorge E Chavarro; Lidia Mínguez-Alarcón; Ramace Dadd; Joseph M Braun; Audrey J Gaskins; John D Meeker; Tamarra James-Todd; Yu-Han Chiu; Feiby L Nassan; Irene Souter; John Petrozza; Myra Keller; Thomas L Toth; Antonia M Calafat; Russ Hauser Journal: Hum Reprod Open Date: 2018-02-20