OBJECTIVES: To review neuroimaging research concerning cancer- and cancer treatment-related changes in brain structure and function, clinical perspectives, and future directions. DATA SOURCES: Peer-reviewed literature. CONCLUSION: Cancer and chemotherapy are associated with cerebral structural and functional alterations in breast cancer patients that may persist for years; many of these changes are correlated with cognitive complaints or performance. In other cancers there is some evidence that metabolism is altered by cancer, but more research is needed. IMPLICATIONS FOR NURSING PRACTICE: Understanding the role of neuroimaging is important to identify the basis of cognitive changes associated with cancer and cancer treatment.
OBJECTIVES: To review neuroimaging research concerning cancer- and cancer treatment-related changes in brain structure and function, clinical perspectives, and future directions. DATA SOURCES: Peer-reviewed literature. CONCLUSION:Cancer and chemotherapy are associated with cerebral structural and functional alterations in breast cancerpatients that may persist for years; many of these changes are correlated with cognitive complaints or performance. In other cancers there is some evidence that metabolism is altered by cancer, but more research is needed. IMPLICATIONS FOR NURSING PRACTICE: Understanding the role of neuroimaging is important to identify the basis of cognitive changes associated with cancer and cancer treatment.
Authors: M Tashiro; F D Juengling; M J Reinhardt; M Mix; H Kumano; K Kubota; M Itoh; H Sasaki; E U Nitzsche; E Moser Journal: Med Sci Monit Date: 2001 Jul-Aug
Authors: Susan K Conroy; Brenna C McDonald; Dori J Smith; Lyndsi R Moser; John D West; Lisa M Kamendulis; James E Klaunig; Victoria L Champion; Frederick W Unverzagt; Andrew J Saykin Journal: Breast Cancer Res Treat Date: 2012-12-22 Impact factor: 4.872
Authors: Michiel B de Ruiter; Liesbeth Reneman; Willem Boogerd; Dick J Veltman; Frits S A M van Dam; Aart J Nederveen; Epie Boven; Sanne B Schagen Journal: Hum Brain Mapp Date: 2010-07-28 Impact factor: 5.038
Authors: Alexandra M Gaynor; Denise Pergolizzi; Yesne Alici; Elizabeth Ryan; Katrazyna McNeal; Tim A Ahles; James C Root Journal: Brain Stimul Date: 2020-04-27 Impact factor: 8.955
Authors: Andrew J Saykin; Michiel B de Ruiter; Brenna C McDonald; Sabine Deprez; Daniel H S Silverman Journal: Brain Imaging Behav Date: 2013-12 Impact factor: 3.978
Authors: Kelly N H Nudelman; Brenna C McDonald; Yang Wang; Dori J Smith; John D West; Darren P O'Neill; Noah R Zanville; Victoria L Champion; Bryan P Schneider; Andrew J Saykin Journal: J Clin Oncol Date: 2015-11-02 Impact factor: 44.544
Authors: Barbara W Carlson; Melissa A Craft; John R Carlson; Wajeeha Razaq; Kelley K Deardeuff; Doris M Benbrook Journal: Geroscience Date: 2018-05-26 Impact factor: 7.713
Authors: Kelly N H Nudelman; Yang Wang; Brenna C McDonald; Susan K Conroy; Dori J Smith; John D West; Darren P O'Neill; Bryan P Schneider; Andrew J Saykin Journal: PLoS One Date: 2014-05-09 Impact factor: 3.240