Literature DB >> 32078618

Pilot Feasibility Study Examining Pupillary Response During Driving Simulation as a Measure of Cognitive Load in Breast Cancer Survivors.

Jamie S Myers1, Nesreen Alissa2, Melissa Mitchell3, Junqiang Dai4, Jianghua He4, Sanghee Moon4, Anne O'Dea5, Jennifer Klemp5, Monica Kurylo4, Abiodun Akinwuntan4, Hannes Devos4.   

Abstract

OBJECTIVES: To test the feasibility of adding driving simulation tasks to measure visuospatial ability and processing speed to an existing neurocognitive battery for breast cancer survivors (BCSs). SAMPLE &
SETTING: 38 BCSs and 17 healthy controls from a cross-sectional pilot study conducted at the University of Kansas Medical Center. METHODS & VARIABLES: Exploratory substudy measuring pupillary response, visuospatial ability, and processing speed during two 10-minute driving simulations (with or without n-back testing) in a sample of BCSs with self-reported cognitive complaints and healthy controls.
RESULTS: Feasibility of measurement of pupillary response during driving simulation was demonstrated. No between-group differences were noted for pupillary response during driving simulation. BCSs had greater visuospatial ability and processing speed performance difficulties than healthy controls during driving simulation without n-back testing and slower n-back response time. IMPLICATIONS FOR NURSING: Preliminary evidence showed a possible link between cancer/treatment on visuospatial ability and processing speed in BCSs.

Entities:  

Keywords:  breast cancer; cognitive dysfunction; driving simulation; pupillary response

Mesh:

Year:  2020        PMID: 32078618      PMCID: PMC7057397          DOI: 10.1188/20.ONF.203-212

Source DB:  PubMed          Journal:  Oncol Nurs Forum        ISSN: 0190-535X            Impact factor:   2.172


  36 in total

1.  Are Driving Simulators Effective Tools for Evaluating Novice Drivers' Hazard Anticipation, Speed Management, and Attention Maintenance Skills.

Authors:  Elsa Chan; Anuj K Pradhan; Alexander Pollatsek; Michael A Knodler; Donald L Fisher
Journal:  Transp Res Part F Traffic Psychol Behav       Date:  2010-09-01

2.  N-back working memory paradigm: a meta-analysis of normative functional neuroimaging studies.

Authors:  Adrian M Owen; Kathryn M McMillan; Angela R Laird; Ed Bullmore
Journal:  Hum Brain Mapp       Date:  2005-05       Impact factor: 5.038

3.  Identifying cognitive state from eye metrics.

Authors:  Sandra P Marshall
Journal:  Aviat Space Environ Med       Date:  2007-05

4.  Effect of simulator training on driving after stroke: a randomized controlled trial.

Authors:  A E Akinwuntan; W De Weerdt; H Feys; J Pauwels; G Baten; P Arno; C Kiekens
Journal:  Neurology       Date:  2005-09-27       Impact factor: 9.910

5.  Pupillary responses to a cognitive effort task in schizophrenia.

Authors:  L Felice Reddy; Eric A Reavis; Jonathan K Wynn; Michael F Green
Journal:  Schizophr Res       Date:  2018-03-09       Impact factor: 4.939

6.  Task-evoked pupillary responses, processing load, and the structure of processing resources.

Authors:  J Beatty
Journal:  Psychol Bull       Date:  1982-03       Impact factor: 17.737

7.  Pupil diameter covaries with BOLD activity in human locus coeruleus.

Authors:  Peter R Murphy; Redmond G O'Connell; Michael O'Sullivan; Ian H Robertson; Joshua H Balsters
Journal:  Hum Brain Mapp       Date:  2014-02-07       Impact factor: 5.038

8.  Disruption of pupil size modulation correlates with voluntary motor preparation deficits in Parkinson's disease.

Authors:  Chin-An Wang; Hailey McInnis; Donald C Brien; Giovanna Pari; Douglas P Munoz
Journal:  Neuropsychologia       Date:  2015-11-26       Impact factor: 3.139

9.  Walking in fully immersive virtual environments: an evaluation of potential adverse effects in older adults and individuals with Parkinson's disease.

Authors:  Aram Kim; Nora Darakjian; James M Finley
Journal:  J Neuroeng Rehabil       Date:  2017-02-21       Impact factor: 4.262

Review 10.  Cancer- and cancer treatment-associated cognitive change: an update on the state of the science.

Authors:  Tim A Ahles; James C Root; Elizabeth L Ryan
Journal:  J Clin Oncol       Date:  2012-09-24       Impact factor: 44.544

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