| Literature DB >> 24182355 |
Jiaoyue Zhang1, Yi Jiang, Yanru Cao, Jiang Liu, Dan Zheng, Xiu Chen, Li Han, Chenglin Jiang, Xueshi Huang.
Abstract
Seven new 3,4,6-trisubstituted α-pyrone derivatives, violapyrones A-G (1-7), were isolated from Streptomyces violascens obtained from Hylobates hoolock feces. Their structures were elucidated on the basis of detailed spectroscopic analysis. The antimicrobial activities of 1-7 were evaluated against Gram-positive and Gram-negative bacteria and against fungi. Compounds 1-3 showed moderate antibacterial activities against Bacillus subtilis and Staphylococcus aureus with MIC values of 4-32 μg/mL.Entities:
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Year: 2013 PMID: 24182355 DOI: 10.1021/np4003417
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050