Literature DB >> 24179920

Primary splenic tubercular abscess in an immunocompromised patient-rapid diagnosis by line probe assay.

Savita V Jadhav1, Chanda R Vyawahare, Nabamita Chaudhari, Neetu S Gupta, Nageswari R Gandham, Rabinadra N Misra.   

Abstract

Diagnosing extra-pulmonary tuberculosis is a challenge that can confound even the most practiced clinicians as clinical manifestations are vague, non-specific and typical chest radiograph findings may not be evident till late in the disease. Conventional methods for mycobacteriological culture and drug susceptibility testing are slow and cumbersome. Novel technologies for rapid detection of Mycobacterium tuberculosis and its anti-TB drug resistance have therefore become a priority hence with the development of molecular line probe assays are most advanced. Herewith we are reporting a case of splenic tuberculosis in an immunocompromised patient for its rarity and to emphasis the fact that such patients can be diagnosed early for better treatment outcome to enhance the longevity if a health setup possesses all the modern diagnostic services.

Entities:  

Keywords:  Extra–pulmonary tuberculosis; Immunocompromised; Line probe assay; Splenic tubercular abscess

Year:  2013        PMID: 24179920      PMCID: PMC3809659          DOI: 10.7860/JCDR/2013/6163.3382

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  10 in total

1.  Case report of lymph nodal, hepatic and splenic tuberculosis in an HIV-positive patient.

Authors:  Bianca Barone; Patrícia Lago Kreuzig; Patricia Medeiros Gusmão; Daniel Chamié; Sabrina Bezerra; Pedro Pinheiro; Pedro Coscarelli; Daurita Paiva; Leila Fonseca; Anna Marsico; André Cirigliano; Mário Perez
Journal:  Braz J Infect Dis       Date:  2006-04       Impact factor: 1.949

2.  Rapid molecular detection of extrapulmonary tuberculosis by the automated GeneXpert MTB/RIF system.

Authors:  Doris Hillemann; Sabine Rüsch-Gerdes; Catharina Boehme; Elvira Richter
Journal:  J Clin Microbiol       Date:  2011-01-26       Impact factor: 5.948

3.  Comparison of enhanced Mycobacterium tuberculosis amplified direct test with COBAS AMPLICOR Mycobacterium tuberculosis assay for direct detection of Mycobacterium tuberculosis complex in respiratory and extrapulmonary specimens.

Authors:  C Scarparo; P Piccoli; A Rigon; G Ruggiero; M Scagnelli; C Piersimoni
Journal:  J Clin Microbiol       Date:  2000-04       Impact factor: 5.948

4.  Clinical significance of splenic tuberculosis in patients infected with human immunodeficiency virus.

Authors:  A González-López; F Dronda; M Alonso-Sanz; F Chaves; I Fernández-Martin; L López-Cubero
Journal:  Clin Infect Dis       Date:  1997-06       Impact factor: 9.079

Review 5.  Extrapulmonary tuberculosis.

Authors:  S K Sharma; A Mohan
Journal:  Indian J Med Res       Date:  2004-10       Impact factor: 2.375

6.  Radiological manifestations of splenic tuberculosis: a 23-patient case series from India.

Authors:  S K Sharma; Duncan Smith-Rohrberg; Mohammad Tahir; Alladi Mohan; Ashu Seith
Journal:  Indian J Med Res       Date:  2007-05       Impact factor: 2.375

Review 7.  Challenges in the diagnosis & treatment of miliary tuberculosis.

Authors:  Surendra K Sharma; Alladi Mohan; Abhishek Sharma
Journal:  Indian J Med Res       Date:  2012-05       Impact factor: 2.375

8.  Primary tuberculous abscess of the spleen in an immununocompetent patient diagnosed by biochemical markers and radiologic findings.

Authors:  Hyung Hun Kim; Seun Ja Park; Moo In Park; Won Moon
Journal:  J Clin Med Res       Date:  2012-03-23

Review 9.  A commercial line probe assay for the rapid detection of rifampicin resistance in Mycobacterium tuberculosis: a systematic review and meta-analysis.

Authors:  Maureen Morgan; Shriprakash Kalantri; Laura Flores; Madhukar Pai
Journal:  BMC Infect Dis       Date:  2005-07-28       Impact factor: 3.090

Review 10.  HIV and tuberculosis in India.

Authors:  Soumya Swaminathan; G Nagendran
Journal:  J Biosci       Date:  2008-11       Impact factor: 2.795

  10 in total

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