Literature DB >> 24179222

Parameter space compression underlies emergent theories and predictive models.

Benjamin B Machta1, Ricky Chachra, Mark K Transtrum, James P Sethna.   

Abstract

The microscopically complicated real world exhibits behavior that often yields to simple yet quantitatively accurate descriptions. Predictions are possible despite large uncertainties in microscopic parameters, both in physics and in multiparameter models in other areas of science. We connect the two by analyzing parameter sensitivities in a prototypical continuum theory (diffusion) and at a self-similar critical point (the Ising model). We trace the emergence of an effective theory for long-scale observables to a compression of the parameter space quantified by the eigenvalues of the Fisher Information Matrix. A similar compression appears ubiquitously in models taken from diverse areas of science, suggesting that the parameter space structure underlying effective continuum and universal theories in physics also permits predictive modeling more generally.

Year:  2013        PMID: 24179222     DOI: 10.1126/science.1238723

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  54 in total

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Authors:  Katherine N Quinn; Colin B Clement; Francesco De Bernardis; Michael D Niemack; James P Sethna
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Authors:  Pratyush Tiwary; B J Berne
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-29       Impact factor: 11.205

7.  Exploring the landscape of model representations.

Authors:  Thomas T Foley; Katherine M Kidder; M Scott Shell; W G Noid
Journal:  Proc Natl Acad Sci U S A       Date:  2020-09-14       Impact factor: 11.205

8.  PCA meets RG.

Authors:  Serena Bradde; William Bialek
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9.  Solvable Model for the Linear Separability of Structured Data.

Authors:  Marco Gherardi
Journal:  Entropy (Basel)       Date:  2021-03-04       Impact factor: 2.524

10.  Phenotype, endotype and patient-specific computational modelling for optimal treatment design in asthma.

Authors:  Graham M Donovan; Merryn H Tawhai
Journal:  Drug Discov Today Dis Models       Date:  2014-04-29
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