| Literature DB >> 24178839 |
Abstract
Following the characterization of a hexadecapeptide,α-endorphin, melanotropin-potentiating factor (MPF) was isolated from the filtrate of uremic patients suffering from melanosis and carbohydrate intolerance. The structure of MPF has been determined on the bases of chemical and physicochemical examinations which included HPLC, Edman sequence analysis combined analysis of the amino acid composition and FAB-MS analysis. An accumulation of MPF might be a cause of melanosis in uremic patients.Entities:
Year: 1995 PMID: 24178839 DOI: 10.1007/BF00805954
Source DB: PubMed Journal: Amino Acids ISSN: 0939-4451 Impact factor: 3.520