| Literature DB >> 24175659 |
Heejun Kim1, Truong Thanh Tung, Seung Bum Park.
Abstract
A new diversity-oriented synthesis pathway for the fabrication of a pyrimidine-embedded polyheterocycles library was developed for potential interactions with diverse biopolymers. Five different pyrimidine-embedded core skeletons were synthesized from ortho-alkynylpyrimidine carbaldehydes by a silver- or iodine-mediated tandem cyclization strategy. The resulting polyheterocycles possess diverse fused ring sizes and positions with potential functionalities for further modification.Entities:
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Year: 2013 PMID： 24175659 DOI： 10.1021/ol402872b
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005