Literature DB >> 24169869

Aggressive plasmablastic multiple myeloma in a 42-year-old: is inflammatory bowel disease or infliximab treatment to be blamed?

Siddhartha Yadav1, Ramesh Kumar, Ishmael A Jaiyesimi, Mohammad Muhsin Chisti.   

Abstract

A man in his early 40s with a history of ulcerative colitis, treated with infliximab, was diagnosed with plasmablastic multiple myeloma. He was treated with chemotherapy and stem cell transplant but developed recurrence and ultimately died from metastatic disease. Could inflammatory bowel disease or infliximab therapy have any role in development of myeloma in this young patient? The role of inflammatory bowel disease and infliximab therapy in the development of multiple myeloma is controversial but interesting and worth considering.

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Year:  2013        PMID: 24169869      PMCID: PMC3822174          DOI: 10.1136/bcr-2013-200607

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  14 in total

Review 1.  Post-transplant plasma cell myeloma and polymorphic lymphoproliferative disorder with monoclonal serum protein occurring in solid organ transplant recipients.

Authors:  Xiaoping Sun; LoAnn C Peterson; Yun Gong; Ann E Traynor; Beverly P Nelson
Journal:  Mod Pathol       Date:  2004-04       Impact factor: 7.842

Review 2.  Genetics of Crohn disease, an archetypal inflammatory barrier disease.

Authors:  Stefan Schreiber; Philip Rosenstiel; Mario Albrecht; Jochen Hampe; Michael Krawczak
Journal:  Nat Rev Genet       Date:  2005-05       Impact factor: 53.242

3.  Association of multiple myeloma and inflammatory bowel diseases.

Authors:  Hong Liu; Jan S Moreb
Journal:  Dig Dis Sci       Date:  2007-08-24       Impact factor: 3.199

4.  Apoptosis-induced by TRAIL AND TNF-alpha in human multiple myeloma cells is not blocked by BCL-2.

Authors:  Y Gazitt; P Shaughnessy; W Montgomery
Journal:  Cytokine       Date:  1999-12       Impact factor: 3.861

5.  Pilot study of recombinant human soluble tumor necrosis factor (TNF) receptor (p75) fusion protein (TNFR:Fc; Enbrel) in patients with refractory multiple myeloma: increase in plasma TNF alpha levels during treatment.

Authors:  Apostolia Maria Tsimberidou; Tracey Waddelow; Hagop M Kantarjian; Maher Albitar; Francis J Giles
Journal:  Leuk Res       Date:  2003-05       Impact factor: 3.156

6.  International staging system for multiple myeloma.

Authors:  Philip R Greipp; Jesus San Miguel; Brian G M Durie; John J Crowley; Bart Barlogie; Joan Bladé; Mario Boccadoro; J Anthony Child; Herve Avet-Loiseau; Jean-Luc Harousseau; Robert A Kyle; Juan J Lahuerta; Heinz Ludwig; Gareth Morgan; Raymond Powles; Kazuyuki Shimizu; Chaim Shustik; Pieter Sonneveld; Patrizia Tosi; Ingemar Turesson; Jan Westin
Journal:  J Clin Oncol       Date:  2005-04-04       Impact factor: 44.544

7.  Survival and causes of death in Italian patients with ulcerative colitis. A GISC nationwide study.

Authors:  A Viscido; V Bagnardi; G C Sturniolo; V Annese; G Frieri; A D'Arienzo; C Papi; G Riegler; G Corrao; R Caprilli
Journal:  Dig Liver Dis       Date:  2001-11       Impact factor: 4.088

8.  Cancer risks in ulcerative colitis patients.

Authors:  Kari Hemminki; Xinjun Li; Jan Sundquist; Kristina Sundquist
Journal:  Int J Cancer       Date:  2008-09-15       Impact factor: 7.396

Review 9.  Review article: multiple myeloma and inflammatory bowel disease.

Authors:  G Joel Reynolds; Kim A Annis; Willem J S de Villiers
Journal:  Dig Dis Sci       Date:  2007-04-10       Impact factor: 3.199

10.  Myeloma in patients younger than age 50 years presents with more favorable features and shows better survival: an analysis of 10 549 patients from the International Myeloma Working Group.

Authors:  Heinz Ludwig; Brian G M Durie; Vanessa Bolejack; Ingemar Turesson; Robert A Kyle; Joan Blade; Rafael Fonseca; Meletios Dimopoulos; Kazuyuki Shimizu; Jesus San Miguel; Jan Westin; Jean-Luc Harousseau; Meral Beksac; Mario Boccadoro; Antonio Palumbo; Bart Barlogie; Chaim Shustik; Michele Cavo; Philip R Greipp; Douglas Joshua; Michel Attal; Pieter Sonneveld; John Crowley
Journal:  Blood       Date:  2008-02-11       Impact factor: 22.113

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