OBJECTIVE: This study evaluates whether or not, among other factors, membrane-coverage of antrostomy defects improves implant survival in sinus augmentation procedures. MATERIALS AND METHODS: We performed a two-arm and split-mouth randomized controlled clinical trial on 104 and 5 patients respectively. In the two-arm study, antrostomy defects were membrane-covered in 66 procedures and uncovered in 69, before placing a total of 265 implants that were followed up for 1 year. In the split-mouth study, following bilateral sinus augmentation, antrostomy defects were membrane-covered on one side and left uncovered on the contra-lateral. Bone biopsies from each sinus were histologically analysed 6 months later. RESULTS: In the two-arm study, implant survival rates were similar (p = 0.08) in the membrane-covered (96.1%) and uncovered (94.2%) groups. In the split-mouth study, bone augmentation was similar in both groups (p = 0.52). Delayed implant placement (p = 0.04), thick Schneider's membrane (≥2 mm) (p < 0.01), treatment for hypertension (p = 0.04) and non-smoking (p = 0.01) seemed to be associated with lower risk of implant failure. CONCLUSIONS:Implant survival in sinus lifting procedures could be influenced significantly by timing of implant placement, Schneider's membrane thickness, antihypertensive treatment and smoking habits, but not by antrostomy membrane coverage.
RCT Entities:
OBJECTIVE: This study evaluates whether or not, among other factors, membrane-coverage of antrostomy defects improves implant survival in sinus augmentation procedures. MATERIALS AND METHODS: We performed a two-arm and split-mouth randomized controlled clinical trial on 104 and 5 patients respectively. In the two-arm study, antrostomy defects were membrane-covered in 66 procedures and uncovered in 69, before placing a total of 265 implants that were followed up for 1 year. In the split-mouth study, following bilateral sinus augmentation, antrostomy defects were membrane-covered on one side and left uncovered on the contra-lateral. Bone biopsies from each sinus were histologically analysed 6 months later. RESULTS: In the two-arm study, implant survival rates were similar (p = 0.08) in the membrane-covered (96.1%) and uncovered (94.2%) groups. In the split-mouth study, bone augmentation was similar in both groups (p = 0.52). Delayed implant placement (p = 0.04), thick Schneider's membrane (≥2 mm) (p < 0.01), treatment for hypertension (p = 0.04) and non-smoking (p = 0.01) seemed to be associated with lower risk of implant failure. CONCLUSIONS: Implant survival in sinus lifting procedures could be influenced significantly by timing of implant placement, Schneider's membrane thickness, antihypertensive treatment and smoking habits, but not by antrostomy membrane coverage.
Authors: Ioannis Tilaveridis; Maria Lazaridou; Lambros Zouloumis; Ioannis Dimitrakopoulos; Vasilis Tilaveridis; Sofia Tilaveridou Journal: Oral Maxillofac Surg Date: 2018-06-01
Authors: Luigi Feletto; Daniele Botticelli; Karol Ali Apaza Alccayhuaman; Miguel Peñarrocha-Diago; Mustafa Ezzeddin-Ayoub; Regino Zaragozi-Alonso; Jose Viña-Almunia Journal: Oral Maxillofac Surg Date: 2022-04-28
Authors: Giacomo Favero; Jose Viña-Almunia; Carmen Carda; José Javier Martín de Llano; Berta García-Mira; David Soto-Peñaloza; Miguel Peñarrocha-Diago; Daniele Botticelli Journal: Int J Implant Dent Date: 2020-03-04
Authors: Carolina Ferrairo Danieletto-Zanna; Vinícius Ferreira Bizelli; Guilherme André Del Arco Ramires; Tamires Melo Francatti; Paulo Sérgio Perri de Carvalho; Ana Paula Farnezi Bassi Journal: Int J Biomater Date: 2020-02-18