Literature DB >> 2416271

Antibacterial activities of antineoplastic agents.

C A Bodet, J H Jorgensen, D J Drutz.   

Abstract

Fourteen antineoplastic agents were examined for in vitro antibacterial activity against 101 aerobic and anaerobic bacterial isolates representing indigenous human microflora and selected opportunistic pathogens. Only 5-fluorouracil, mitomycin, and etoposide demonstrated inhibitory effects at achievable plasma concentrations, while the remaining drugs lacked appreciable antibacterial activities.

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Year:  1985        PMID: 2416271      PMCID: PMC180269          DOI: 10.1128/AAC.28.3.437

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  13 in total

1.  PHASE I clinical trial of an oral solution of VP-16-213.

Authors:  N I Nissen; P Dombernowsky; H H Hansen; V Larsen
Journal:  Cancer Treat Rep       Date:  1976-07

2.  Bactericidal effect of combinations of antimicrobial drugs and antineoplastic antibiotics against Staphylococcus aureus.

Authors:  J Y Jacobs; J Michel; T Sacks
Journal:  Antimicrob Agents Chemother       Date:  1979-04       Impact factor: 5.191

3.  Relapsing pseudomembranous colitis associated with cancer chemotherapy.

Authors:  V Fainstein; G P Bodey; R Fekety
Journal:  J Infect Dis       Date:  1981-06       Impact factor: 5.226

4.  Tabular summary of pharmacokinetic parameters relevant to in vitro drug assay.

Authors:  D S Alberts; H S Chen
Journal:  Prog Clin Biol Res       Date:  1980

5.  Colonization resistance of the digestive tract in conventional and antibiotic-treated mice.

Authors:  D van der Waaij; J M Berghuis-de Vries
Journal:  J Hyg (Lond)       Date:  1971-09

6.  Bactericidal effect of combinations of antimicrobial drugs and antineoplastic antibiotics against gram-negative bacilli.

Authors:  J Michel; J Y Jacobs; T Sacks
Journal:  Antimicrob Agents Chemother       Date:  1979-12       Impact factor: 5.191

7.  Effect of chemotherapeutic agents upon microorganisms isolated from cancer patients.

Authors:  M C Goldschmidt; G P Bodey
Journal:  Antimicrob Agents Chemother       Date:  1972-04       Impact factor: 5.191

8.  Staphylococcus epidermidis: an increasing cause of infection in patients with granulocytopenia.

Authors:  J C Wade; S C Schimpff; K A Newman; P H Wiernik
Journal:  Ann Intern Med       Date:  1982-10       Impact factor: 25.391

9.  Clostridium difficile colitis associated with cancer chemotherapy.

Authors:  M A Cudmore; J Silva; R Fekety; M K Liepman; K H Kim
Journal:  Arch Intern Med       Date:  1982-02

10.  Antimicrobial activity of 21 anti-neoplastic agents.

Authors:  J M Hamilton-Miller
Journal:  Br J Cancer       Date:  1984-03       Impact factor: 7.640

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  19 in total

Review 1.  Drug-gut microbiota interactions: implications for neuropharmacology.

Authors:  Jacinta Walsh; Brendan T Griffin; Gerard Clarke; Niall P Hyland
Journal:  Br J Pharmacol       Date:  2018-06-28       Impact factor: 8.739

2.  16S rRNA gene pyrosequencing reveals shift in patient faecal microbiota during high-dose chemotherapy as conditioning regimen for bone marrow transplantation.

Authors:  Emmanuel Montassier; Eric Batard; Sébastien Massart; Thomas Gastinne; Thomas Carton; Jocelyne Caillon; Sophie Le Fresne; Nathalie Caroff; Jean Benoit Hardouin; Philippe Moreau; Gilles Potel; Françoise Le Vacon; Marie France de La Cochetière
Journal:  Microb Ecol       Date:  2014-01-09       Impact factor: 4.552

3.  Host genetic susceptibility to Clostridium difficile infections in patients undergoing autologous stem cell transplantation: a genome-wide association study.

Authors:  Senu Apewokin; Jeannette Y Lee; Julia A Goodwin; Kent D McKelvey; Owen W Stephens; Daohong Zhou; Elizabeth Ann Coleman
Journal:  Support Care Cancer       Date:  2018-03-28       Impact factor: 3.603

Review 4.  A "Double-Edged" Scaffold: Antitumor Power within the Antibacterial Quinolone.

Authors:  Gregory S Bisacchi; Michael R Hale
Journal:  Curr Med Chem       Date:  2016       Impact factor: 4.530

Review 5.  The interplay between anticancer challenges and the microbial communities from the gut.

Authors:  Olivier Tenaillon; André Birgy; Claire Amaris Hobson; Stéphane Bonacorsi; André Baruchel
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2022-03-30       Impact factor: 5.103

6.  Factors affecting colonization and dissemination of Candida albicans from the gastrointestinal tract of mice.

Authors:  O Ekenna; R J Sherertz
Journal:  Infect Immun       Date:  1987-07       Impact factor: 3.441

7.  Antimicrobial activity of cytotoxic drugs may influence isolation of bacteria and fungi from blood cultures.

Authors:  V Peiris; B A Oppenheim
Journal:  J Clin Pathol       Date:  1993-12       Impact factor: 3.411

8.  Systems toxicology study of doxorubicin on rats using ultra performance liquid chromatography coupled with mass spectrometry based metabolomics.

Authors:  Jiangshan Wang; Theo Reijmers; Lijuan Chen; Rob Van Der Heijden; Mei Wang; Shuangqing Peng; Thomas Hankemeier; Guowang Xu; Jan Van Der Greef
Journal:  Metabolomics       Date:  2009-05-21       Impact factor: 4.290

9.  5-Fluorouracil blocks quorum-sensing of biofilm-embedded methicillin-resistant Staphylococcus aureus in mice.

Authors:  Ferdinand Sedlmayer; Anne-Kathrin Woischnig; Vincent Unterreiner; Florian Fuchs; Daniel Baeschlin; Nina Khanna; Martin Fussenegger
Journal:  Nucleic Acids Res       Date:  2021-07-21       Impact factor: 19.160

10.  Impact of extensive antibiotic treatment on faecal carriage of antibiotic-resistant enterobacteria in children in a low resistance prevalence setting.

Authors:  Per Kristian Knudsen; Petter Brandtzaeg; E Arne Høiby; Jon Bohlin; Ørjan Samuelsen; Martin Steinbakk; Tore G Abrahamsen; Fredrik Müller; Karianne Wiger Gammelsrud
Journal:  PLoS One       Date:  2017-11-07       Impact factor: 3.240

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