| Literature DB >> 24161954 |
M A Rahman1, A Salajegheh, R A Smith, A K-Y Lam.
Abstract
B-Raf is one of the more commonly mutated proto-oncogenes implicated in the development of cancers. In this review, we consider the mechanisms and clinical impacts of B-Raf mutations in cancer and discuss the implications for the patient in melanoma, thyroid cancer and colorectal cancer, where B-Raf mutations are particularly common.Entities:
Keywords: B-Raf; BRAF; Colorectal cancer; Melanoma; Mutation; Thyroid cancer
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Year: 2013 PMID： 24161954 DOI： 10.1016/j.yexmp.2013.10.005
Source DB: PubMed Journal: Exp Mol Pathol ISSN： 0014-4800 Impact factor: 3.362