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Literature DB >> 24158240

γ-AApeptide-based small-molecule ligands that inhibit Aβ aggregation.

Haifan Wu¹, Yaqiong Li, Ge Bai, Youhong Niu, Qiao Qiao, Jeremiah D Tipton, Chuanhai Cao, Jianfeng Cai.

Abstract

We report the design, synthesis, characterization and evaluation of a novel class of γ-AApeptide one-bead-one-compound (OBOC) library, from which a small γ-AApeptide was identified to effectively prevent and disassemble Aβ aggregation.

Entities: Disease

Mesh：

Substances：

Year: 2013 PMID： 24158240 DOI： 10.1039/c3cc46685j

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

13 in total

1. Polycarbonates with Potent and Selective Antimicrobial Activity toward Gram-Positive Bacteria.

Authors: Alekhya Nimmagadda; Xuan Liu; Peng Teng; Ma Su; Yaqiong Li; Qiao Qiao; Nawal K Khadka; Xiaoting Sun; Jianjun Pan; Hai Xu; Qi Li; Jianfeng Cai
Journal: Biomacromolecules Date: 2016-12-08 Impact factor: 6.988

2. γ-AApeptides: Design, Structure, and Applications.

Authors: Yan Shi; Peng Teng; Peng Sang; Fengyu She; Lulu Wei; Jianfeng Cai
Journal: Acc Chem Res Date: 2016-02-22 Impact factor: 22.384

3. Aggregation-Induced Emissive and Circularly Polarized Homogeneous Sulfono-γ-AApeptide Foldamers.

Authors: Yan Shi; Peng Sang; Guangqiang Yin; Ruixuan Gao; Xiao Liang; Robert Brzozowski; Timothy Odom; Prahathees Eswara; Youxuan Zheng; Xiaopeng Li; Jianfeng Cai
Journal: Adv Opt Mater Date: 2020-04-20 Impact factor: 9.926

Review 4. Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs.

Authors: Natalia Molchanova; Paul R Hansen; Henrik Franzyk
Journal: Molecules Date: 2017-08-29 Impact factor: 4.411

5. Recognition of antigen-specific B-cell receptors from chronic lymphocytic leukemia patients by synthetic antigen surrogates.

Authors: Mohosin Sarkar; Yun Liu; Jumpei Morimoto; Haiyong Peng; Claudio Aquino; Christoph Rader; Nicholas Chiorazzi; Thomas Kodadek
Journal: Chem Biol Date: 2014-11-26

Review 6. Antimicrobial AApeptides.

Authors: Peng Sang; Yan Shi; Peng Teng; Annie Cao; Hai Xu; Qi Li; Jianfeng Cai
Journal: Curr Top Med Chem Date: 2017 Impact factor: 3.295

γ-AApeptide-based small-molecule ligands that inhibit Aβ aggregation.

1. Polycarbonates with Potent and Selective Antimicrobial Activity toward Gram-Positive Bacteria.

2. γ-AApeptides: Design, Structure, and Applications.

3. Aggregation-Induced Emissive and Circularly Polarized Homogeneous Sulfono-γ-AApeptide Foldamers.

Review 4. Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs.

5. Recognition of antigen-specific B-cell receptors from chronic lymphocytic leukemia patients by synthetic antigen surrogates.

Review 6. Antimicrobial AApeptides.

7. One-Bead-Two-Compound Thioether Bridged Macrocyclic γ-AApeptide Screening Library against EphA2.

8. Identification of novel inhibitors that disrupt STAT3-DNA interaction from a γ-AApeptide OBOC combinatorial library.

9. γ-AApeptides as a New Class of Peptidomimetics.

10. Short antimicrobial lipo-α/γ-AA hybrid peptides.