Literature DB >> 2415713

Novel 2',5'-oligoadenylates synthesized in interferon-treated, vaccinia virus-infected cells.

A P Rice, S M Kerr, W K Roberts, R E Brown, I M Kerr.   

Abstract

2-5A[ppp(A2'p)nA] and related materials accumulate to greater than micromolar concentrations in vaccinia virus-infected HeLa cells and in interferon-treated, vaccinia-infected HeLa, CV1, and L929 cells even when virus replication is not inhibited. A variably complex mixture of authentic 2-5A (n = 2 to 4), nonphosphorylated cores [(A2'p)nA; n = 2 to 5], and additional compounds of unknown structure was observed.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 2415713      PMCID： PMC252683     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  16 in total

1.  Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells.

Authors:  M Knight; P J Cayley; R H Silverman; D H Wreschner; C S Gilbert; R E Brown; I M Kerr
Journal:  Nature       Date:  1980-11-13       Impact factor: 49.962

2.  Degradation of rRNA in interferon-treated vaccinia virus-infected cells.

Authors:  B B Goswami; O K Sharma
Journal:  J Biol Chem       Date:  1984-02-10       Impact factor: 5.157

Review 3.  Biochemistry of interferons and their actions.

Authors:  P Lengyel
Journal:  Annu Rev Biochem       Date:  1982       Impact factor: 23.643

4.  Analysis of (2'-5')-oligo(A) and related oligonucleotides by high-performance liquid chromatography.

Authors:  R E Brown; P J Cayley; I M Kerr
Journal:  Methods Enzymol       Date:  1981       Impact factor: 1.600

5.  Synthesis, characterisation and biological significance of (2'-5')oligoadenylate derivatives of NAD+, ADP-ribose and adenosine(5')tetraphospho(5')adenosine.

Authors:  P J Cayley; I M Kerr
Journal:  Eur J Biochem       Date:  1982-03-01

6.  The 2'5' oligoadenylate synthetase has a multifunctional 2'5' nucleotidyl-transferase activity.

Authors:  D Ferbus; J Justesen; F Besançon; M N Thang
Journal:  Biochem Biophys Res Commun       Date:  1981-05-29       Impact factor: 3.575

7.  Preparation, characterization, and use of an antiserum specific for 2',5'-oligoadenylates.

Authors:  C L Hersh; T R Reid; R Friedman; G R Stark
Journal:  J Biol Chem       Date:  1984-02-10       Impact factor: 5.157

8.  Analogues and analogue inhibitors of ppp(A2'p)nA. Their stability and biological activity.

Authors:  M C Haugh; P J Cayley; H T Serafinowska; D G Norman; C B Reese; I M Kerr
Journal:  Eur J Biochem       Date:  1983-04-15

9.  Activation of the ppp(A2'p)nA system in interferon-treated, herpes simplex virus-infected cells and evidence for novel inhibitors of the ppp(A2'p)nA-dependent RNase.

Authors:  P J Cayley; J A Davies; K G McCullagh; I M Kerr
Journal:  Eur J Biochem       Date:  1984-08-15

10.  Indiscriminate degradation of RNAs in interferon-treated, vaccinia virus-infected mouse L cells.

Authors:  J Benavente; E Paez; M Esteban
Journal:  J Virol       Date:  1984-09       Impact factor: 5.103
View more
  11 in total

Review 1.  A scientific journey through the 2-5A/RNase L system.

Authors:  Robert H Silverman
Journal:  Cytokine Growth Factor Rev       Date:  2007-07-27       Impact factor: 7.638

Review 2.  Viral encounters with 2',5'-oligoadenylate synthetase and RNase L during the interferon antiviral response.

Authors:  Robert H Silverman
Journal:  J Virol       Date:  2007-09-05       Impact factor: 5.103

3.  Modulation of ppp(A2'p)nA-dependent RNase by a temperature-sensitive mutant of vaccinia virus.

Authors:  R J Cohrs; R C Condit; R F Pacha; C L Thompson; O K Sharma
Journal:  J Virol       Date:  1989-02       Impact factor: 5.103

Review 4.  Viral phosphodiesterases that antagonize double-stranded RNA signaling to RNase L by degrading 2-5A.

Authors:  Robert H Silverman; Susan R Weiss
Journal:  J Interferon Cytokine Res       Date:  2014-06       Impact factor: 2.607

Review 5.  Poxvirus pathogenesis.

Authors:  R M Buller; G J Palumbo
Journal:  Microbiol Rev       Date:  1991-03

6.  Small-molecule activators of RNase L with broad-spectrum antiviral activity.

Authors:  Chandar S Thakur; Babal Kant Jha; Beihua Dong; Jaydip Das Gupta; Kenneth M Silverman; Hongxia Mao; Hiro Sawai; Akiko O Nakamura; Amiya K Banerjee; Andrei Gudkov; Robert H Silverman
Journal:  Proc Natl Acad Sci U S A       Date:  2007-05-29       Impact factor: 11.205

7.  Evasion of antiviral innate immunity by Theiler's virus L* protein through direct inhibition of RNase L.

Authors:  Frédéric Sorgeloos; Babal Kant Jha; Robert H Silverman; Thomas Michiels
Journal:  PLoS Pathog       Date:  2013-06-27       Impact factor: 6.823

Review 8.  Can't RIDD off viruses.

Authors:  Sankar Bhattacharyya
Journal:  Front Microbiol       Date:  2014-06-18       Impact factor: 5.640

Review 9.  Inhibition of the OAS/RNase L pathway by viruses.

Authors:  Melissa Drappier; Thomas Michiels
Journal:  Curr Opin Virol       Date:  2015-07-29       Impact factor: 7.090

Review 10.  The 2-5A system: modulation of viral and cellular processes through acceleration of RNA degradation.

Authors:  M R Player; P F Torrence
Journal:  Pharmacol Ther       Date:  1998-05       Impact factor: 12.310
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.