Literature DB >> 24156517

Tubular polymersomes: a cross-linker-induced shape transformation.

Matthijs C M van Oers1, Floris P J T Rutjes, Jan C M van Hest.   

Abstract

Polymersomes, polymeric vesicles constructed of block copolymers, can undergo a sphere-to-tubule transition under the influence of a chemical modification of the polymeric bilayer. A strain-promoted alkyne-azide cycloaddition (SPAAC) reaction between azide handles inside the hydrophobic domain of the membrane and an excess of a bicyclo[6.1.0]nonyne (BCN)-cross-linker causes the vesicle to stretch in one dimension. Tubular polymersomes up to 2 μm in length can be obtained with this shape transformation. The introduction of a cleavable cross-linker makes this process reversible and opens the way for future drug delivery applications.

Entities:  

Year:  2013        PMID： 24156517     DOI： 10.1021/ja408754z

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  16 in total

1.  Facile assembly and loading of theranostic polymersomes via multi-impingement flash nanoprecipitation.

Authors:  Sean Allen; Omar Osorio; Yu-Gang Liu; Evan Scott
Journal:  J Control Release       Date:  2017-07-20       Impact factor: 9.776

Review 2.  Combining Nanoparticle Shape Modulation and Polymersome Technology in Drug Delivery.

Authors:  Cara Katterman; Christopher Pierce; Jessica Larsen
Journal:  ACS Appl Bio Mater       Date:  2021-03-08

Review 3.  Engineering Polymersomes for Diagnostics and Therapy.

Authors:  Jiayu Leong; Jye Yng Teo; Vinay K Aakalu; Yi Yan Yang; Hyunjoon Kong
Journal:  Adv Healthc Mater       Date:  2018-01-15       Impact factor: 9.933

4.  Modulating Shape of Polyester Based Polymersomes using Osmotic Pressure.

Authors:  Christopher Pierce; Cara Katterman; Jessica Larsen
Journal:  J Vis Exp       Date:  2021-04-21       Impact factor: 1.424

5.  Shaping polymersomes into predictable morphologies via out-of-equilibrium self-assembly.

Authors:  R S M Rikken; H Engelkamp; R J M Nolte; J C Maan; J C M van Hest; D A Wilson; P C M Christianen
Journal:  Nat Commun       Date:  2016-08-25       Impact factor: 14.919

6.  Formation of non-spherical polymersomes driven by hydrophobic directional aromatic perylene interactions.

Authors:  Chin Ken Wong; Alexander F Mason; Martina H Stenzel; Pall Thordarson
Journal:  Nat Commun       Date:  2017-11-01       Impact factor: 14.919

7.  Stimulus-responsive block copolymer nano-objects and hydrogels via dynamic covalent chemistry.

Authors:  Renhua Deng; Yin Ning; Elizabeth R Jones; Victoria J Cunningham; Nicholas J W Penfold; Steven P Armes
Journal:  Polym Chem       Date:  2017-07-28       Impact factor: 5.582

8.  Using Dynamic Covalent Chemistry To Drive Morphological Transitions: Controlled Release of Encapsulated Nanoparticles from Block Copolymer Vesicles.

Authors:  Renhua Deng; Matthew J Derry; Charlotte J Mable; Yin Ning; Steven P Armes
Journal:  J Am Chem Soc       Date:  2017-05-23       Impact factor: 15.419

Review 9.  Biosynthetic Polymers as Functional Materials.

Authors:  Andrea S Carlini; Lisa Adamiak; Nathan C Gianneschi
Journal:  Macromolecules       Date:  2016-06-21       Impact factor: 5.985

10.  Formation of Well-Defined, Functional Nanotubes via Osmotically Induced Shape Transformation of Biodegradable Polymersomes.

Authors:  Loai K E A Abdelmohsen; David S Williams; Jan Pille; Sema G Ozel; Roger S M Rikken; Daniela A Wilson; Jan C M van Hest
Journal:  J Am Chem Soc       Date:  2016-07-21       Impact factor: 15.419
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