Literature DB >> 2415214

Dopamine inhibition of neurotensin-induced increase in Ca2+ influx into rat pituitary cells.

M Memo, E Carboni, M Trabucchi, M O Carruba, P F Spano.   

Abstract

In this paper, we report that the intracellular mechanism by which neurotensin stimulates prolactin release involves an increase in Ca2+ uptake by pituitary cells rather than an effect on adenylate cyclase system. In addition, dopamine can prevent neurotensin-induced calcium influx by interacting with dopamine D2-receptors which appear to be completely independent of the adenylate cyclase moiety but are coupled to calcium channels.

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Year:  1985        PMID： 2415214     DOI： 10.1016/0006-8993(85)90184-2

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  5 in total

1.  B-HT 920 activates dopamine D2 receptors coupled to inhibition of adenylate cyclase activity.

Authors:  P Onali; M C Olianas
Journal:  J Neural Transm Gen Sect       Date:  1992

Review 2.  Pharmacological and molecular basis for dopamine D-2 receptor diversity.

Authors:  M Memo
Journal:  Mol Neurobiol       Date:  1990 Fall-Winter       Impact factor: 5.590

3.  Dopamine D-2 receptors inhibit D-1 stimulated cyclic AMP accumulation in striatum but not limbic forebrain.

Authors:  E Kelly; S R Nahorski
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-05       Impact factor: 3.000

4.  Potassium channels involved in the transduction mechanism of dopamine D2 receptors in rat lactotrophs.

Authors:  L Castelletti; M Memo; C Missale; P F Spano; A Valerio
Journal:  J Physiol       Date:  1989-03       Impact factor: 5.182

5.  Neurotensin stimulates inositol trisphosphate-mediated calcium mobilization but not protein kinase C activation in HT29 cells. Involvement of a G-protein.

Authors:  J C Bozou; N Rochet; I Magnaldo; J P Vincent; P Kitabgi
Journal:  Biochem J       Date:  1989-12-15       Impact factor: 3.857
  5 in total

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