Literature DB >> 24150812

Epigenetics of Alzheimer's disease and frontotemporal dementia.

Chendhore S Veerappan1, Sama Sleiman, Giovanni Coppola.   

Abstract

This article will review the recent advances in the understanding of the role of epigenetic modifications and the promise of future epigenetic therapy in neurodegenerative dementias, including Alzheimer's disease and frontotemporal dementia.

Entities:  

Mesh：

Year:  2013        PMID： 24150812      PMCID： PMC3805876          DOI： 10.1007/s13311-013-0219-0

Source DB:  PubMed          Journal:  Neurotherapeutics        ISSN： 1878-7479            Impact factor:   7.620


  149 in total

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2.  Alzheimer's disease biomarkers and epigenetic intermediates following exposure to Pb in vitro.

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Review 4.  The potential of HDAC inhibitors as cognitive enhancers.

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7.  MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1.

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Review 8.  "Seq-ing" insights into the epigenetics of neuronal gene regulation.

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9.  An epigenetic blockade of cognitive functions in the neurodegenerating brain.

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Journal:  Nature       Date:  2012-02-29       Impact factor: 49.962

10.  Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity.

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Journal:  Neuron       Date:  2008-12-10       Impact factor: 17.173
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  14 in total

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Review 2.  Amyotrophic lateral sclerosis: mechanisms and therapeutics in the epigenomic era.

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Review 5.  Epigenetics of Aging and Alzheimer's Disease: Implications for Pharmacogenomics and Drug Response.

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Review 6.  ALS and FTD: an epigenetic perspective.

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Review 7.  Epigenetic Therapeutics: A New Weapon in the War Against Cancer.

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8.  Accelerated epigenetic age and cognitive decline among urban-dwelling adults.

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Review 9.  Dissecting Alzheimer disease in Down syndrome using mouse models.

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Review 10.  Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders.

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