Luca Buzzonetti1, Paolo Capozzi, Gianni Petrocelli, Paola Valente, Sergio Petroni, Luca Menabuoni, Francesca Rossi, Roberto Pini. 1. From the Ophthalmology Departments, Bambino Gesù Children's Hospital (Buzzonetti, Capozzi, Petrocelli, Valente, Petroni), IRCCS, Rome, and Misericordia e Dolce Hospital (Menabuoni), Prato, and Istituto di Fisica Applicata Nello Carrara (Rossi, Pini), Italian National Research Council, Sesto Fiorentino, Florence, Italy. Electronic address: lucabuzzonetti@yahoo.it.
Abstract
PURPOSE: To evaluate the efficacy of diode laser welding to close corneal wounds in penetrating keratoplasty (PKP) and cataract surgery in pediatric patients. SETTING: Ophthalmology Department, Bambino Gesù Children's Hospital, Rome, Italy. DESIGN: Prospective observational study. METHODS: Patients had surgery for congenital cataract (Group 1) or femtosecond laser-assisted PKP (Group 2). The surgery was followed by corneal wound closure using diode laser welding of the stroma. In Group 1, no standard suturing was used. In Group 2, the donor button was sutured onto the recipient using 8 single nylon sutures or a 10-0 nylon running suture (12 passages). Laser welding was then used as an adjunct to the traditional suturing procedure. RESULTS: Group 1 comprised 7 eyes (7 patients; mean age 8.1 years ± 5.3 [SD], range 1 to 15 years) and Group 2, 5 eyes (5 patients; mean age 10.6 ± 3.3 years, range 6 to 15 years). The adhesion of the laser-welded tissues was perfect; there were no collateral effects, and restoration of the treated tissues was optimum. Seidel testing showed no wound leakage during the follow-up. Postoperative astigmatism did not change significantly from the first day after cataract surgery and shifted moderately 3 months after PKP. CONCLUSION: Laser welding of corneal tissue appeared to be safe and effective in children for whom a sutureless surgical procedure is important to reduce the use of anesthesia for suture management, prevent endophthalmitis, and improve the antiamblyopic effect.
PURPOSE: To evaluate the efficacy of diode laser welding to close corneal wounds in penetrating keratoplasty (PKP) and cataract surgery in pediatric patients. SETTING: Ophthalmology Department, Bambino Gesù Children's Hospital, Rome, Italy. DESIGN: Prospective observational study. METHODS:Patients had surgery for congenital cataract (Group 1) or femtosecond laser-assisted PKP (Group 2). The surgery was followed by corneal wound closure using diode laser welding of the stroma. In Group 1, no standard suturing was used. In Group 2, the donor button was sutured onto the recipient using 8 single nylon sutures or a 10-0 nylon running suture (12 passages). Laser welding was then used as an adjunct to the traditional suturing procedure. RESULTS: Group 1 comprised 7 eyes (7 patients; mean age 8.1 years ± 5.3 [SD], range 1 to 15 years) and Group 2, 5 eyes (5 patients; mean age 10.6 ± 3.3 years, range 6 to 15 years). The adhesion of the laser-welded tissues was perfect; there were no collateral effects, and restoration of the treated tissues was optimum. Seidel testing showed no wound leakage during the follow-up. Postoperative astigmatism did not change significantly from the first day after cataract surgery and shifted moderately 3 months after PKP. CONCLUSION: Laser welding of corneal tissue appeared to be safe and effective in children for whom a sutureless surgical procedure is important to reduce the use of anesthesia for suture management, prevent endophthalmitis, and improve the antiamblyopic effect.
Authors: Svetlana Basov; Amit Milstein; Erez Sulimani; Max Platkov; Eli Peretz; Marcel Rattunde; Joachim Wagner; Uri Netz; Abraham Katzir; Ilana Nisky Journal: Biomed Opt Express Date: 2018-10-19 Impact factor: 3.732
Authors: Luca Pagano; Haider Shah; Omar Al Ibrahim; Kunal A Gadhvi; Giulia Coco; Jason W Lee; Stephen B Kaye; Hannah J Levis; Kevin J Hamill; Francesco Semeraro; Vito Romano Journal: J Clin Med Date: 2022-02-18 Impact factor: 4.241