Literature DB >> 24136291

Short-term outcome of patients with ST-segment elevation myocardial infarction (STEMI) treated with an everolimus-eluting bioresorbable vascular scaffold.

Jens Wiebe1, Helge Möllmann, Astrid Most, Oliver Dörr, Kay Weipert, Johannes Rixe, Christoph Liebetrau, Albrecht Elsässer, Stephan Achenbach, Christian Hamm, Holger Nef.   

Abstract

OBJECTIVES: To evaluate safety and efficacy of the everolimus-eluting bioresorbable scaffold (BVS) in patients with ST-segment elevation myocardial infarction (STEMI).
BACKGROUND: According to the current guidelines, drug-eluting stents are the treatment of choice in patients with STEMI. BVS represents a new technology capable to restore the native vessel vasomotion and potentially avoiding long-term limitations such as stent thrombosis.
METHODS: From October 2012 to May 2013, patients with evidence of STEMI eligible for BVS implantation were included in this study. Exclusion criteria were not defined.
RESULTS: A total of 25 patients, respectively 31 lesions, were treated. Procedural success was achieved in 97%. Two major adverse cardiac events occurred during hospitalization and follow-up: one patient with cardiogenic shock at the index procedure subsequently died. One patient suffered from instable angina with need for interventional revascularization of a previously untreated vessel. One target vessel failure as a consequence of an intra-procedural dissection was seen. However, no target lesion failure was noted. During 132.7 ± 68.7 days of follow-up none of the patients died.
CONCLUSION: Our findings suggest that implantation of BVS in STEMI patients is feasible in this small cohort of highly selected patients. Further evaluation in randomized-controlled trials is needed.

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Year:  2013        PMID: 24136291     DOI: 10.1007/s00392-013-0630-x

Source DB:  PubMed          Journal:  Clin Res Cardiol        ISSN: 1861-0684            Impact factor:   5.460


  49 in total

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Journal:  Clin Res Cardiol       Date:  2010-10-24       Impact factor: 5.460

2.  Everolimus-eluting versus sirolimus-eluting stents: an updated meta-analysis of randomized trials.

Authors:  Antoinette de Waha; Salvatore Cassese; Duk-Woo Park; Francesco Burzotta; Robert A Byrne; Tomohisa Tada; Lamin A King; Seung-Jung Park; Albert Schömig; Adnan Kastrati
Journal:  Clin Res Cardiol       Date:  2012-03-16       Impact factor: 5.460

3.  Outcome of percutaneous coronary intervention with drug-eluting stents in unprotected left main versus non-left main native coronary artery disease: results from the prospective multicenter German DES.DE registry.

Authors:  I Akin; C Naber; G Sabin; M Hochadel; J Senges; K H Kuck; C Nienaber; G Richardt; Ralph Tölg
Journal:  Clin Res Cardiol       Date:  2013-05-17       Impact factor: 5.460

4.  Impact of hyperglycemia at admission in patients with acute ST-segment elevation myocardial infarction as assessed by contrast-enhanced MRI.

Authors:  Christoph J Jensen; Holger C Eberle; Kai Nassenstein; Thomas Schlosser; Mani Farazandeh; Christoph K Naber; Georg V Sabin; Oliver Bruder
Journal:  Clin Res Cardiol       Date:  2011-02-24       Impact factor: 5.460

5.  Intracoronary versus intravenous bolus abciximab application in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: 6-month effects on infarct size and left ventricular function. The randomised Leipzig Immediate PercutaneouS Coronary Intervention Abciximab i.v. versus i.c. in ST-Elevation Myocardial Infarction Trial (LIPSIAbciximab-STEMI).

Authors:  Ingo Eitel; Josef Friedenberger; Georg Fuernau; Annett Dumjahn; Steffen Desch; Gerhard Schuler; Holger Thiele
Journal:  Clin Res Cardiol       Date:  2010-12-02       Impact factor: 5.460

6.  Efficacy and safety of a high loading dose of clopidogrel administered prehospitally to improve primary percutaneous coronary intervention in acute myocardial infarction: the randomized CIPAMI trial.

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Journal:  Clin Res Cardiol       Date:  2011-12-21       Impact factor: 5.460

7.  In vivo evaluation of stent strut distribution patterns in the bioabsorbable everolimus-eluting device: an OCT ad hoc analysis of the revision 1.0 and revision 1.1 stent design in the ABSORB clinical trial.

Authors:  Takayuki Okamura; Scot Garg; Juan Luis Gutiérrez-Chico; Eun-Seok Shin; Yoshinobu Onuma; Héctor M García-García; Richard J Rapoza; Krishnankutty Sudhir; Evelyn Regar; Patrick W Serruys
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8.  TNF-α, myocardial perfusion and function in patients with ST-segment elevation myocardial infarction and primary percutaneous coronary intervention.

Authors:  Eva S Kehmeier; Wolfgang Lepper; Martina Kropp; Christian Heiss; Ulrike Hendgen-Cotta; Jan Balzer; Mirja Neizel; Christian Meyer; Marc W Merx; Pablo E Verde; Christian Ohmann; Gerd Heusch; Malte Kelm; Tienush Rassaf
Journal:  Clin Res Cardiol       Date:  2012-05-06       Impact factor: 5.460

Review 9.  Long-term clinical outcomes following sirolimus-eluting stent implantation in patients with acute myocardial infarction. A meta-analysis of randomized trials.

Authors:  Raffaele Piccolo; Salvatore Cassese; Gennaro Galasso; Tullio Niglio; Roberta De Rosa; Chiara De Biase; Federico Piscione
Journal:  Clin Res Cardiol       Date:  2012-05-16       Impact factor: 5.460

10.  Cost-effectiveness of ticagrelor versus clopidogrel for the prevention of atherothrombotic events in adult patients with acute coronary syndrome in Germany.

Authors:  Ulrike Theidel; Christian Asseburg; Evangelos Giannitsis; Hugo Katus
Journal:  Clin Res Cardiol       Date:  2013-03-09       Impact factor: 5.460

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  15 in total

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Journal:  Clin Res Cardiol       Date:  2013-12-28       Impact factor: 5.460

2.  A potential life-threatening complication after implantation of a bioresorbable scaffold for coronary stenting within a mechanically stressed region.

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Journal:  Clin Res Cardiol       Date:  2015-01-20       Impact factor: 5.460

Review 3.  Contemporary management of ST-segment elevation myocardial infarction.

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4.  Safety of percutaneous coronary intervention in patients with acute ischemic stroke/transient ischemic attack and acute coronary syndrome.

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5.  Successful ablation of a bioresorbable polymeric vascular scaffold by rotational atherectomy.

Authors:  Stefan Wagner; M Hünlich; G Hasenfuß; C Jacobshagen
Journal:  Clin Res Cardiol       Date:  2014-03-04       Impact factor: 5.460

Review 6.  Acute revascularization in ST-segment-elevation myocardial infarction.

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Review 7.  Bioresorbable vascular scaffolds - basic concepts and clinical outcome.

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8.  The Bioresorbable Stent in Perspective-How Much of an Advance is It?

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Review 9.  Are acute coronary syndromes an ideal scenario for bioresorbable vascular scaffold implantation?

Authors:  Elisabetta Moscarella; Alfonso Ielasi; Maria Carmen De Angelis; Fortunato Scotto di Uccio; Enrico Cerrato; Roberta De Rosa; Gianluca Campo; Attilio Varricchio
Journal:  J Thorac Dis       Date:  2017-08       Impact factor: 2.895

10.  Bioresorbable vascular scaffolds-time to vanish?

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Journal:  J Thorac Dis       Date:  2016-06       Impact factor: 2.895

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