Literature DB >> 24133335

Optimization of multiple muco-cutaneous site sampling method for screening MRSA colonization in ICU.

Priya Datta1, Hena Rani Vasdeva, Jagdish Chander.   

Abstract

AIMS: Active screening for methicillin resistant Staphylococcus aureus (MRSA) carriers remains a vital component of infection control policy in any health-care setting. The relative advantage of multiple anatomical site screening for detecting MRSA carriers is well recognized. However, this leads to increase in financial and logistical load in a developing world scenario. The objective of our study was to determine the sensitivity of MRSA screening of nose, throat, axilla, groin, perineum and the site of catheterization (central line catheter) individually among intensive care unit patients and to compare it with the sensitivity of multiple site screening.
MATERIALS AND METHODS: Active surveillance of 400 patients was done to detect MRSA colonization; 6 sites-nose, throat, axilla, perineum, groin and site of catheter were swabbed. RESULT AND DISCUSSION: The throat swab alone was able to detect maximum number of MRSA (76/90) carriers, with sensitivity of 84.4%. Next in order of sensitivity was nasal swab, which tested 77.7% of MRSA colonized patients. When multiple sites are screened, the sensitivity for MRSA detection increased to 95%.
CONCLUSIONS: We found that though throat represent the most common site of MRSA colonization, nose or groin must also be sampled simultaneously to attain a higher sensitivity.

Entities:  

Keywords:  Asymptomatic colonization; intensive care unit; methicillin resistant Staphylococcus aureus colonization

Year:  2013        PMID: 24133335      PMCID: PMC3796906          DOI: 10.4103/0972-5229.118421

Source DB:  PubMed          Journal:  Indian J Crit Care Med        ISSN: 0972-5229


  11 in total

1.  Screening for methicillin-resistant Staphylococcus aureus: which anatomical sites to culture?

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2.  Re: is throat screening necessary to detect methicillin-resistant Staphylococcus aureus colonization in patients upon admission to an intensive care unit?

Authors:  Caroline Marshall; Denis Spelman
Journal:  J Clin Microbiol       Date:  2007-08-29       Impact factor: 5.948

3.  Selective screening of carriers for control of methicillin-resistant Staphylococcus aureus (MRSA) in high-risk hospital areas with a high level of endemic MRSA.

Authors:  E Girou; G Pujade; P Legrand; F Cizeau; C Brun-Buisson
Journal:  Clin Infect Dis       Date:  1998-09       Impact factor: 9.079

4.  Efficient detection and long-term persistence of the carriage of methicillin-resistant Staphylococcus aureus.

Authors:  M D Sanford; A F Widmer; M J Bale; R N Jones; R P Wenzel
Journal:  Clin Infect Dis       Date:  1994-12       Impact factor: 9.079

5.  Staphylococcus aureus throat colonization is more frequent than colonization in the anterior nares.

Authors:  Peter Nilsson; Torvald Ripa
Journal:  J Clin Microbiol       Date:  2006-09       Impact factor: 5.948

6.  Comparison of systematic versus selective screening for methicillin-resistant Staphylococcus aureus carriage in a high-risk dermatology ward.

Authors:  E Girou; J Azar; P Wolkenstein; F Cizeau; C Brun-Buisson; J C Roujeau
Journal:  Infect Control Hosp Epidemiol       Date:  2000-09       Impact factor: 3.254

7.  Evaluation of various methods for the detection of meticillin-resistant Staphylococcus aureus strains and susceptibility patterns.

Authors:  Priya Datta; Neelam Gulati; Nidhi Singla; Hena Rani Vasdeva; Kiran Bala; Jagdish Chander; Varsha Gupta
Journal:  J Med Microbiol       Date:  2011-07-21       Impact factor: 2.472

8.  Surveillance cultures for detection of methicillin-resistant Staphylococcus aureus: diagnostic yield of anatomic sites and comparison of provider- and patient-collected samples.

Authors:  Ebbing Lautenbach; Irving Nachamkin; Baofeng Hu; Neil O Fishman; Pam Tolomeo; Priya Prasad; Warren B Bilker; Theoklis E Zaoutis
Journal:  Infect Control Hosp Epidemiol       Date:  2009-04       Impact factor: 3.254

9.  Routine screening for methicillin-resistant Staphylococcus aureus among patients newly admitted to an acute rehabilitation unit.

Authors:  Farrin A Manian; Diane Senkel; Jeanne Zack; Lynn Meyer
Journal:  Infect Control Hosp Epidemiol       Date:  2002-09       Impact factor: 3.254

10.  Prevalence and risk factors for carriage of methicillin-resistant Staphylococcus aureus at admission to the intensive care unit: results of a multicenter study.

Authors:  Jean-Christophe Lucet; Sylvie Chevret; Isabelle Durand-Zaleski; Claude Chastang; Bernard Régnier
Journal:  Arch Intern Med       Date:  2003-01-27
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  7 in total

1.  Evaluation of sampling locations in pregnant women and newborns for the detection of colonisation with antibiotic-resistant bacteria.

Authors:  M Zamfir; A C Adler; S Kolb; A Dammeyer; L Nasri; L Schomacher; B Karlin; M Franitza; S Hörmansdorfer; C Tuschak; G Valenza; U Ochmann; C Herr
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2017-05-04       Impact factor: 3.267

2.  Occurrence of methicillin-resistant Staphylococcus aureus in farm workers and the livestock environment in Mecklenburg-Western Pomerania, Germany.

Authors:  Carmen Dahms; Nils-Olaf Hübner; Christiane Cuny; Axel Kramer
Journal:  Acta Vet Scand       Date:  2014-08-21       Impact factor: 1.695

Review 3.  Methicillin-resistant Staphylococcus aureus multiple sites surveillance: a systemic review of the literature.

Authors:  John Chipolombwe; Mili Estee Török; Nontombi Mbelle; Peter Nyasulu
Journal:  Infect Drug Resist       Date:  2016-02-12       Impact factor: 4.003

4.  Heavy metal exposure and nasal Staphylococcus aureus colonization: analysis of the National Health and Nutrition Examination Survey (NHANES).

Authors:  Shoshannah Eggers; Nasia Safdar; Kristen Mc Malecki
Journal:  Environ Health       Date:  2018-01-05       Impact factor: 5.984

5.  Multidrug-Resistant Klebsiella pneumoniae in a Patient with SARS-Cov-2 Pneumonia in an Intensive Care Unit in Guayaquil, Ecuador: A Case Report.

Authors:  Betty J Pazmiño Gómez; Jennifer P Rodas Pazmiño; Gabriel S González Quinde; Jorge F Guevara Viejó; Miguel J Merejildo Amaguaña; Édgar I Rodas Neira; Francisco A Rizzo Rodríguez; Luis E Cagua Montaño; Karen A Rodas Pazmiño
Journal:  Am J Case Rep       Date:  2022-07-22

6.  The evaluation of MRSA surveillance cultures by the number and combinations of anatomical sites.

Authors:  Irena Grmek Kosnik; Alenka Storman; Ziva Petrovic; Slavica Robnik; Urska Dermota; Tjasa Zohar Cretnik
Journal:  Zdr Varst       Date:  2016-07-28

Review 7.  Methicillin-resistant Staphylococcus aureus in Intensive Care Unit Setting of India: A Review of Clinical Burden, Patterns of Prevalence, Preventive Measures, and Future Strategies.

Authors:  Yatin Mehta; Ashit Hegde; Rajesh Pande; Kapil G Zirpe; Varsha Gupta; Jaishid Ahdal; Amit Qamra; Salman Motlekar; Rishi Jain
Journal:  Indian J Crit Care Med       Date:  2020-01
  7 in total

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