Literature DB >> 24131688

Role of pncA and rpsA gene sequencing in detection of pyrazinamide resistance in Mycobacterium tuberculosis isolates from southern China.

Yaoju Tan1, Zuqiong Hu, Tianyu Zhang, Xingshan Cai, Haobin Kuang, Yanwen Liu, Junyu Chen, Feng Yang, Ke Zhang, Shouyong Tan, Yanlin Zhao.   

Abstract

We sequenced pncA and rpsA genes plus flanking regions of 161 Mycobacterium tuberculosis isolates and found 10 new pncA and 3 novel rpsA mutations in pyrazinamide-resistant strains determined by the Bactec MGIT 960 system. The 3' end of rpsA might be added as the target of molecular detection of pyrazinamide susceptibility.

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Year:  2013        PMID： 24131688      PMCID： PMC3911430          DOI： 10.1128/JCM.01903-13

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  33 in total

1.  pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates from northwestern Russia.

Authors:  H J Marttila; M Marjamäki; E Vyshnevskaya; B I Vyshnevskiy; T F Otten; A V Vasilyef; M K Viljanen
Journal:  Antimicrob Agents Chemother       Date:  1999-07       Impact factor: 5.191

2.  Correlation between pyrazinamide activity and pncA mutations in Mycobacterium tuberculosis isolates in Taiwan.

Authors:  Tsi-Shu Huang; Susan Shin-Jung Lee; Hui-Zin Tu; Wen-Kuei Huang; Yao-Shen Chen; Chung-Kai Huang; Shue-Ren Wann; Hsi-Hsun Lin; Yung-Ching Liu
Journal:  Antimicrob Agents Chemother       Date:  2003-11       Impact factor: 5.191

3.  pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates in Portugal.

Authors:  Isabel Portugal; Luís Barreiro; José Moniz-Pereira; Laura Brum
Journal:  Antimicrob Agents Chemother       Date:  2004-07       Impact factor: 5.191

4.  Mycobacterium smegmatis has two pyrazinamidase enzymes, PncA and pzaA.

Authors:  M Guo; Z Sun; Y Zhang
Journal:  J Bacteriol       Date:  2000-07       Impact factor: 3.490

5.  Pyrazinamide sterilizing activity in vitro against semidormant Mycobacterium tuberculosis bacterial populations.

Authors:  L Heifets; P Lindholm-Levy
Journal:  Am Rev Respir Dis       Date:  1992-05

6.  Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis.

Authors:  A Scorpio; P Lindholm-Levy; L Heifets; R Gilman; S Siddiqi; M Cynamon; Y Zhang
Journal:  Antimicrob Agents Chemother       Date:  1997-03       Impact factor: 5.191

Review 7.  The curious characteristics of pyrazinamide: a review.

Authors:  Y Zhang; D Mitchison
Journal:  Int J Tuberc Lung Dis       Date:  2003-01       Impact factor: 2.373

8.  Mutations in pncA, a gene encoding pyrazinamidase/nicotinamidase, cause resistance to the antituberculous drug pyrazinamide in tubercle bacillus.

Authors:  A Scorpio; Y Zhang
Journal:  Nat Med       Date:  1996-06       Impact factor: 53.440

9.  Mutation in pncA is a major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis.

Authors:  K Hirano; M Takahashi; Y Kazumi; Y Fukasawa; C Abe
Journal:  Tuber Lung Dis       Date:  1997

10.  pncA mutations in clinical Mycobacterium tuberculosis isolates from Korea.

Authors:  S K Park; J Y Lee; C L Chang; M K Lee; H C Son; C M Kim; H J Jang; H K Park; S H Jeong
Journal:  BMC Infect Dis       Date:  2001-06-20       Impact factor: 3.090
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  39 in total

Review 1.  Antibiotic resistance mechanisms in M. tuberculosis: an update.

Authors:  Liem Nguyen
Journal:  Arch Toxicol       Date:  2016-05-09       Impact factor: 5.153

Review 2.  Pharmacological and Molecular Mechanisms Behind the Sterilizing Activity of Pyrazinamide.

Authors:  Pooja Gopal; Gerhard Grüber; Véronique Dartois; Thomas Dick
Journal:  Trends Pharmacol Sci       Date:  2019-11-06       Impact factor: 14.819

Review 3.  The Bewildering Antitubercular Action of Pyrazinamide.

Authors:  Elise A Lamont; Nicholas A Dillon; Anthony D Baughn
Journal:  Microbiol Mol Biol Rev       Date:  2020-03-04       Impact factor: 11.056

4.  Phenotypic and genotypic characterization of pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis isolates in Zhejiang, China.

Authors:  Qiang Xia; Li-Li Zhao; Feng Li; Yu-Mei Fan; Yuan-Yuan Chen; Bei-Bei Wu; Zheng-Wei Liu; Ai-Zhen Pan; Min Zhu
Journal:  Antimicrob Agents Chemother       Date:  2015-01-12       Impact factor: 5.191

5.  Direct Detection of Pyrazinamide Resistance in Mycobacterium tuberculosis by Use of pncA PCR Sequencing.

Authors:  Kingsley King-Gee Tam; Kenneth Siu-Sing Leung; Gilman Kit-Hang Siu; Kwok-Chiu Chang; Samson Sai-Yin Wong; Pak-Leung Ho; Eunice Ka-Chun Leung; Wing-Cheong Yam
Journal:  J Clin Microbiol       Date:  2019-07-26       Impact factor: 5.948

6.  Introducing RpsA Point Mutations Δ438A and D123A into the Chromosome of Mycobacterium tuberculosis Confirms Their Role in Causing Resistance to Pyrazinamide.

Authors:  Wanliang Shi; Peng Cui; Hongxia Niu; Shuo Zhang; Tone Tønjum; Bingdong Zhu; Ying Zhang
Journal:  Antimicrob Agents Chemother       Date:  2019-05-24       Impact factor: 5.191

7.  Prevalence and transmission of pyrazinamide resistant Mycobacterium tuberculosis in China.

Authors:  Peng Xu; Jie Wu; Chongguang Yang; Tao Luo; Xin Shen; Yangyi Zhang; Chijioke A Nsofor; Guofeng Zhu; Brigitte Gicquel; Qian Gao
Journal:  Tuberculosis (Edinb)       Date:  2016-03-03       Impact factor: 3.131

8.  Design, Synthesis, and Biological Evaluation of Pyrazolo[1,5-a]pyridine-3-carboxamides as Novel Antitubercular Agents.

Authors:  Jian Tang; Bangxing Wang; Tian Wu; Junting Wan; Zhengchao Tu; Moses Njire; Baojie Wan; Scott G Franzblauc; Tianyu Zhang; Xiaoyun Lu; Ke Ding
Journal:  ACS Med Chem Lett       Date:  2015-06-11       Impact factor: 4.345

9.  Pyrazinoic Acid Inhibits a Bifunctional Enzyme in Mycobacterium tuberculosis.

Authors:  Moses Njire; Na Wang; Bangxing Wang; Yaoju Tan; Xingshan Cai; Yanwen Liu; Julius Mugweru; Jintao Guo; H M Adnan Hameed; Shouyong Tan; Jianxiong Liu; Wing Wai Yew; Eric Nuermberger; Gyanu Lamichhane; Jinsong Liu; Tianyu Zhang
Journal:  Antimicrob Agents Chemother       Date:  2017-06-27       Impact factor: 5.191

10.  Multicenter Study of the Emergence and Genetic Characteristics of Pyrazinamide-Resistant Tuberculosis in China.

Authors:  Dange Li; Yi Hu; Jim Werngren; Mikael Mansjö; Xubin Zheng; Francis Drobniewski; Sven Hoffner; Biao Xu
Journal:  Antimicrob Agents Chemother       Date:  2016-08-22       Impact factor: 5.191
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