| Literature DB >> 2412871 |
C K Lumpkin, J K McClung, J R Smith.
Abstract
Initiation of DNA synthesis was inhibited in human fibroblasts following microinjection with poly(A)+RNA derived from normal rat liver. After sucrose gradient sedimentation of the RNA, the inhibitory activity was found to be limited to two adjacent fractions. Dilution experiments suggest a minimum abundance level of 0.015% for this mRNA(s). Studies on the kinetics of this inhibition indicate a reversible inhibition with a duration of approx. 10 h.Entities:
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Year: 1985 PMID： 2412871 DOI： 10.1016/0014-4827(85)90201-0
Source DB: PubMed Journal: Exp Cell Res ISSN： 0014-4827 Impact factor: 3.905