Literature DB >> 3785220

Mitogenic effects of the proto-oncogene and oncogene forms of c-H-ras DNA in human diploid fibroblasts.

C K Lumpkin, J E Knepper, J S Butel, J R Smith, O M Pereira-Smith.   

Abstract

Nuclear microinjection of c-H-ras DNA induced DNA synthesis in reversibly nonproliferating quiescent human cells. The proto-oncogene and oncogene forms were equally effective inducers. In contrast, c-H-ras DNA either alone or in combination with the adenovirus E1A gene did not cause terminally nondividing senescent cells to synthesize DNA.

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Year:  1986        PMID： 3785220      PMCID： PMC367870          DOI： 10.1128/mcb.6.8.2990-2993.1986

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  35 in total

1.  THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS.

Authors:  L HAYFLICK
Journal:  Exp Cell Res       Date:  1965-03       Impact factor: 3.905

2.  Doubling potential, calendar time, and senescence of human diploid cells in culture.

Authors:  R T Dell'Orco; J G Mertens; P F Kruse
Journal:  Exp Cell Res       Date:  1973-03-15       Impact factor: 3.905

3.  Entry into S phase is inhibited in two immortal cell lines fused to senescent human diploid cells.

Authors:  G H Stein; R M Yanishevsky
Journal:  Exp Cell Res       Date:  1979-04       Impact factor: 3.905

4.  Expression of SV40 T antigen in finite life-span hybrids of normal and SV40-transformed fibroblasts.

Authors:  O M Pereira-Smith; J R Smith
Journal:  Somatic Cell Genet       Date:  1981-07

5.  Isolation of a transforming sequence from a human bladder carcinoma cell line.

Authors:  C Shih; R A Weinberg
Journal:  Cell       Date:  1982-05       Impact factor: 41.582

6.  Characterization of cells transformed by Ad5/Ad12 hybrid early region I plasmids.

Authors:  R Bernards; A Houweling; P I Schrier; J L Bos; A J Van der Eb
Journal:  Virology       Date:  1982-07-30       Impact factor: 3.616

7.  Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change.

Authors:  E Taparowsky; Y Suard; O Fasano; K Shimizu; M Goldfarb; M Wigler
Journal:  Nature       Date:  1982-12-23       Impact factor: 49.962

8.  Carcinogen-transformed human cells are inhibited from entry into S phase by fusion to senescent cells but cells transformed by DNA tumor viruses overcome the inhibition.

Authors:  G H Stein; R M Yanishevsky; L Gordon; M Beeson
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

9.  Localization of the src gene product of the Harvey strain of MSV to plasma membrane of transformed cells by electron microscopic immunocytochemistry.

Authors:  M C Willingham; I Pastan; T Y Shih; E M Scolnick
Journal:  Cell       Date:  1980-04       Impact factor: 41.582

10.  Evidence for endogenous polypeptide-mediated inhibition of cell-cycle transit in human diploid cells.

Authors:  G C Burmer; C J Zeigler; T H Norwood
Journal:  J Cell Biol       Date:  1982-07       Impact factor: 10.539
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  13 in total

1.  Reversal of human cellular senescence: roles of the p53 and p16 pathways.

Authors:  Christian M Beauséjour; Ana Krtolica; Francesco Galimi; Masashi Narita; Scott W Lowe; Paul Yaswen; Judith Campisi
Journal:  EMBO J       Date:  2003-08-15       Impact factor: 11.598

2.  Senescent cells fail to express cdc2, cycA, and cycB in response to mitogen stimulation.

Authors:  G H Stein; L F Drullinger; R S Robetorye; O M Pereira-Smith; J R Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-15       Impact factor: 11.205

Review 3.  Control of myogenic differentiation by cellular oncogenes.

Authors:  M D Schneider; E N Olson
Journal:  Mol Neurobiol       Date:  1988       Impact factor: 5.590

4.  An activated c-Ha-ras allele blocks the induction of muscle-specific genes whose expression is contingent on mitogen withdrawal.

Authors:  P A Payne; E N Olson; P Hsiau; R Roberts; M B Perryman; M D Schneider
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

5.  An overexpressed gene transcript in senescent and quiescent human fibroblasts encoding a novel protein in the epidermal growth factor-like repeat family stimulates DNA synthesis.

Authors:  B Lecka-Czernik; C K Lumpkin; S Goldstein
Journal:  Mol Cell Biol       Date:  1995-01       Impact factor: 4.272

6.  Differential expression of the ras gene family in mice.

Authors:  J Leon; I Guerrero; A Pellicer
Journal:  Mol Cell Biol       Date:  1987-04       Impact factor: 4.272

7.  The ras-like yeast YPT1 gene is itself essential for growth, sporulation, and starvation response.

Authors:  N Segev; D Botstein
Journal:  Mol Cell Biol       Date:  1987-07       Impact factor: 4.272

8.  Targeting of the rasT24 oncogene to the proximal convoluted tubules in transgenic mice results in hyperplasia and polycystic kidneys.

Authors:  D L Schaffner; R Barrios; C Massey; E I Bañez; C N Ou; S Rajagopalan; E Aguilar-Cordova; R M Lebovitz; P A Overbeek; M W Lieberman
Journal:  Am J Pathol       Date:  1993-04       Impact factor: 4.307

9.  Chronic NF-kappaB activation delays RasV12-induced premature senescence of human fibroblasts by suppressing the DNA damage checkpoint response.

Authors:  Christina Batsi; Soultana Markopoulou; George Vartholomatos; Ioannis Georgiou; Panagiotis Kanavaros; Vassilis G Gorgoulis; Kenneth B Marcu; Evangelos Kolettas
Journal:  Mech Ageing Dev       Date:  2009-05-03       Impact factor: 5.432

10.  Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling.

Authors:  A W Lin; M Barradas; J C Stone; L van Aelst; M Serrano; S W Lowe
Journal:  Genes Dev       Date:  1998-10-01       Impact factor: 11.361
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