Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Biochemical properties of a penicillin beta-lactamase mediated by R factor from Bordetella bronchiseptica.

Literature DB >> 241286

Biochemical properties of a penicillin beta-lactamase mediated by R factor from Bordetella bronchiseptica.

Abstract

The beta-lactamase specified by an R(te16) plasmid in Bordetella bronchiseptica was purified 200-fold by carboxymethyl-Sephadex column chromatography and electrofocusing. The enzyme has a molecular weight of 46,000 +/- 3,000 and an isoelectric point of 8.3 and was highly active against phenethicillin, oxacillin, and propicillin. The enzyme activity was inhibited by sodium chloride but not by ferrous ion. The maximal enzyme activity to benzylpenicillin was observed at pH 7.0 to 7.5 and at 40 C. It is concluded that this enzyme is different from the R-mediated beta-lactamases, i.e., the type I and type II beta-lactamases which have been classified in previous papers.

Entities: Chemical Species

Mesh：

Substances：

Year: 1975 PMID： 241286 PMCID： PMC429300 DOI： 10.1128/AAC.8.3.238

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

16 in total

Review 1. The beta-lactamases of gram-negative bacteria and their possible physiological role.

Authors: M H Richmond; R B Sykes
Journal: Adv Microb Physiol Date: 1973 Impact factor: 3.517

2. Variant of penicillinase mediated by an R factor in Escherichia coli.

Authors: T Sawai; K Takahashi; S Yamagishi; S Mitsuhashi
Journal: J Bacteriol Date: 1970-11 Impact factor: 3.490

3. Drug resistance and its transfer in Salmonella typhimurium.

Authors: E S Anderson; M J Lewis
Journal: Nature Date: 1965-05-08 Impact factor: 49.962

4. Drug resistance of enteric bacteria. XIV. Comparison of beta-lactamases in gram-negative rod bacteria resistant to alpha-aminobenzylpenicillin.

Authors: T Sawai; S Mitsuhashi; S Yamagishi
Journal: Jpn J Microbiol Date: 1968-12

5. The purification and properties of penicillin beta-lactamases mediated by transmissible R factors in Escherichia coli.

Authors: S Yamagishi; K O'Hara; T Sawai; S Mitsuhashi
Journal: J Biochem Date: 1969-07 Impact factor: 3.387

6. Characterization of the -lactamase specified by the resistance factor R-1818 in E. coli K12 and other Gram-negative bacteria.

Authors: J W Dale
Journal: Biochem J Date: 1971-07 Impact factor: 3.857

7. The purification and properties of the -lactamase specified by the resistance factor R-1818 in Escherichia coli and Proteus mirabilis.

Authors: J W Dale; J T Smith
Journal: Biochem J Date: 1971-07 Impact factor: 3.857

8. Resistance of Escherichia coli to penicillins. VII. Purification and characterization of a penicillinase mediated by the R factor R1.

Authors: R C Lindqvist; K Nordström
Journal: J Bacteriol Date: 1970-01 Impact factor: 3.490

9. Demonstration of R factors in Bordetella bronchiseptica isolated from pigs.

Authors: N Terakado; H Azechi; K Ninomiya; T Shimizu
Journal: Antimicrob Agents Chemother Date: 1973-05 Impact factor: 5.191

10. Estimation of the molecular weights of proteins by Sephadex gel-filtration.

Authors: P Andrews
Journal: Biochem J Date: 1964-05 Impact factor: 3.766

14 in total

1. Plasmid-mediated penicillin beta-lactamases in Pseudomonas aeruginosa.

Authors: Y Sawada; S Yaginuma; M Tai; S Iyobe; S Mitsuhashi
Journal: Antimicrob Agents Chemother Date: 1976-01 Impact factor: 5.191

Review 2. Drug resistance plasmids.

Authors: S Mitsuhashi
Journal: Mol Cell Biochem Date: 1979-08-15 Impact factor: 3.396

Biochemical properties of a penicillin beta-lactamase mediated by R factor from Bordetella bronchiseptica.

Review 1. The beta-lactamases of gram-negative bacteria and their possible physiological role.

2. Variant of penicillinase mediated by an R factor in Escherichia coli.

3. Drug resistance and its transfer in Salmonella typhimurium.

4. Drug resistance of enteric bacteria. XIV. Comparison of beta-lactamases in gram-negative rod bacteria resistant to alpha-aminobenzylpenicillin.

5. The purification and properties of penicillin beta-lactamases mediated by transmissible R factors in Escherichia coli.

6. Characterization of the -lactamase specified by the resistance factor R-1818 in E. coli K12 and other Gram-negative bacteria.

7. The purification and properties of the -lactamase specified by the resistance factor R-1818 in Escherichia coli and Proteus mirabilis.

8. Resistance of Escherichia coli to penicillins. VII. Purification and characterization of a penicillinase mediated by the R factor R1.

9. Demonstration of R factors in Bordetella bronchiseptica isolated from pigs.

10. Estimation of the molecular weights of proteins by Sephadex gel-filtration.

1. Plasmid-mediated penicillin beta-lactamases in Pseudomonas aeruginosa.

Review 2. Drug resistance plasmids.

3. Types of beta-lactamase determined by plasmids in gram-negative bacteria.

4. Properties of the beta-lactamase specified by the Pseudomonas plasmid RPL11.

5. Purification and properties of inducible penicillin beta-lactamase isolated from Pseudomonas maltophilia.

Review 6. Biology of Bordetella bronchiseptica.

7. In vitro and in vivo antibacterial activity of T-1220, a new semisynthetic penicillin.

8. In vitro studies on the antibacterial activities of YM-13115, a new broad-spectrum cephalosporin.

9. Antimicrobial activity and stability to beta-lactamase of BMY-28271, a new oral cephalosporin ester.

10. Properties of novel beta-lactamase produced by Bacteroides fragilis.