Literature DB >> 24121427

A highly sensitive long-wavelength fluorescence probe for nitroreductase and hypoxia: selective detection and quantification.

Ting Guo1, Lei Cui, Jiaoning Shen, Weiping Zhu, Yufang Xu, Xuhong Qian.   

Abstract

A novel long-wavelength fluorescence probe has been developed for the detection of nitroreductase (NTR) and hypoxia. could be activated by NTR at 0.1 μM to release the fluorophore and significant changes in fluorescence emission at 658 nm were observed. This feature makes it advantageous for imaging hypoxic cells with minimal endogenous interference.

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Year:  2013        PMID： 24121427     DOI： 10.1039/c3cc45367g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

1.  In Vivo Chemiluminescent Imaging Agents for Nitroreductase and Tissue Oxygenation.

Authors:  Jian Cao; James Campbell; Li Liu; Ralph P Mason; Alexander R Lippert
Journal:  Anal Chem       Date:  2016-04-15       Impact factor: 6.986

2.  Luminescent Probe Based Techniques for Hypoxia Imaging.

Authors:  Sana Sandhu; LeNaiya Kydd; Justyn Jaworski
Journal:  J Nanomed Res       Date:  2017-11-20

3.  Nitroreductase-triggered activation of a novel caged fluorescent probe obtained from methylene blue.

Authors:  Jungeun Bae; Louis E McNamara; Manal A Nael; Fakhri Mahdi; Robert J Doerksen; Gene L Bidwell; Nathan I Hammer; Seongbong Jo
Journal:  Chem Commun (Camb)       Date:  2015-08-18       Impact factor: 6.222

4.  Benzimidazole Based 'Turn on' Fluorescent Chemodosimeter for Zinc Ions in Mixed Aqueous Medium.

Authors:  Shilpa Sharma; Chullikkattil P Pradeep; Abhimanew Dhir
Journal:  J Fluoresc       Date:  2016-06-04       Impact factor: 2.217

5.  Azo-Based Iridium(III) Complexes as Multicolor Phosphorescent Probes to Detect Hypoxia in 3D Multicellular Tumor Spheroids.

Authors:  Lingli Sun; Guanying Li; Xiang Chen; Yu Chen; Chengzhi Jin; Liangnian Ji; Hui Chao
Journal:  Sci Rep       Date:  2015-10-01       Impact factor: 4.379

6.  Hypoxia-triggered single molecule probe for high-contrast NIR II/PA tumor imaging and robust photothermal therapy.

Authors:  Xiaoqing Meng; Jiali Zhang; Zhihong Sun; Lihua Zhou; Guanjun Deng; Sanpeng Li; Wenjun Li; Ping Gong; Lintao Cai
Journal:  Theranostics       Date:  2018-11-15       Impact factor: 11.556

7.  An Activatable Near-Infrared Chromophore for Multispectral Optoacoustic Imaging of Tumor Hypoxia and for Tumor Inhibition.

Authors:  Jing Huang; Yinglong Wu; Fang Zeng; Shuizhu Wu
Journal:  Theranostics       Date:  2019-09-25       Impact factor: 11.556

8.  A fast-responsive fluorescent turn-on probe for nitroreductase imaging in living cells.

Authors:  Chengli Jia; Yong Zhang; Yuesong Wang; Min Ji
Journal:  RSC Adv       Date:  2021-02-24       Impact factor: 3.361

9.  Novel designed azo substituted semi-cyanine fluorescent probe for cytochrome P450 reductase detection and hypoxia imaging in cancer cells.

Authors:  Caiyue Wang; Shuping Zhang; Junhai Huang; Lei Cui; Jin Hu; Shaoying Tan
Journal:  RSC Adv       Date:  2019-07-11       Impact factor: 4.036

10.  A molecular design strategy toward enzyme-activated probes with near-infrared I and II fluorescence for targeted cancer imaging.

Authors:  Rongchen Wang; Jian Chen; Jie Gao; Ji-An Chen; Ge Xu; Tianli Zhu; Xianfeng Gu; Zhiqian Guo; Wei-Hong Zhu; Chunchang Zhao
Journal:  Chem Sci       Date:  2019-06-14       Impact factor: 9.825
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