Literature DB >> 24112429

Exposures to molds in school classrooms of children with asthma.

Sachin N Baxi1, Michael L Muilenberg, Christine A Rogers, William J Sheehan, Jonathan Gaffin, Perdita Permaul, Lianne S Kopel, Peggy S Lai, Jeffrey P Lane, Ann Bailey, Carter R Petty, Chunxia Fu, Diane R Gold, Wanda Phipatanakul.   

Abstract

BACKGROUND: Students spend a large portion of their day in classrooms which may be a source of mold exposure. We examined the diversity and concentrations of molds in inner-city schools and described differences between classrooms within the same school.
METHODS: Classroom airborne mold spores, collected over a 2 day period, were measured twice during the school year by direct microscopy.
RESULTS: There were 180 classroom air samples collected from 12 schools. Mold was present in 100% of classrooms. Classrooms within the same school had differing mold levels and mold diversity scores. The total mold per classroom was 176.6 ± 4.2 spores/m3 (geometric mean ± standard deviation) and ranged from 11.2 to 16,288.5 spores/m3. Mold diversity scores for classroom samples ranged from 1 to 19 (7.7 ± 3.5). The classroom accounted for the majority of variance (62%) in the total mold count, and for the majority of variance (56%) in the mold diversity score versus the school. The species with the highest concentrations and found most commonly included Cladosporium (29.3 ± 4.2 spores/m3), Penicillium/Aspergillus (15.0 ± 5.4 spores/m3), smut spores (12.6 ± 4.0 spores/m3), and basidiospores (6.6 ± 7.1 spores/m3).
CONCLUSIONS: Our study found that the school is a source of mold exposure, but particularly the classroom microenvironment varies in quantity of spores and species among classrooms within the same school. We also verified that visible mold may be a predictor for higher mold spore counts. Further studies are needed to determine the clinical significance of mold exposure relative to asthma morbidity in sensitized and non-sensitized asthmatic children.
© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  asthma; children; fungus; inner-city; mold; school

Mesh:

Substances:

Year:  2013        PMID: 24112429      PMCID: PMC3782748          DOI: 10.1111/pai.12127

Source DB:  PubMed          Journal:  Pediatr Allergy Immunol        ISSN: 0905-6157            Impact factor:   6.377


  34 in total

1.  Fungal Fragments in Moldy Houses: A Field Study in Homes in New Orleans and Southern Ohio.

Authors:  Tiina Reponen; Sung-Chul Seo; Faye Grimsley; Taekhee Lee; Carlos Crawford; Sergey A Grinshpun
Journal:  Atmos Environ (1994)       Date:  2007-12       Impact factor: 4.798

2.  Daily asthma severity in relation to personal ozone exposure and outdoor fungal spores.

Authors:  R J Delfino; B D Coate; R S Zeiger; J M Seltzer; D H Street; P Koutrakis
Journal:  Am J Respir Crit Care Med       Date:  1996-09       Impact factor: 21.405

Review 3.  Airborne fungal fragments and allergenicity.

Authors:  Brett J Green; Euan R Tovey; Jason K Sercombe; Francoise M Blachere; Donald H Beezhold; Detlef Schmechel
Journal:  Med Mycol       Date:  2006-09       Impact factor: 4.076

Review 4.  The link between fungi and severe asthma: a summary of the evidence.

Authors:  D W Denning; B R O'Driscoll; C M Hogaboam; P Bowyer; R M Niven
Journal:  Eur Respir J       Date:  2006-03       Impact factor: 16.671

5.  Effect of environmental molds on risk of death from asthma during the pollen season.

Authors:  P V Targonski; V W Persky; V Ramekrishnan
Journal:  J Allergy Clin Immunol       Date:  1995-05       Impact factor: 10.793

6.  Exposure to Alternaria alternata in US homes is associated with asthma symptoms.

Authors:  Päivi M Salo; Samuel J Arbes; Michelle Sever; Renee Jaramillo; Richard D Cohn; Stephanie J London; Darryl C Zeldin
Journal:  J Allergy Clin Immunol       Date:  2006-10       Impact factor: 10.793

7.  Fungal DNA, allergens, mycotoxins and associations with asthmatic symptoms among pupils in schools from Johor Bahru, Malaysia.

Authors:  Gui-Hong Cai; Jamal Hisham Hashim; Zailina Hashim; Faridah Ali; Erica Bloom; Lennart Larsson; Erik Lampa; Dan Norbäck
Journal:  Pediatr Allergy Immunol       Date:  2011-05       Impact factor: 6.377

8.  Infant origins of childhood asthma associated with specific molds.

Authors:  Tiina Reponen; James Lockey; David I Bernstein; Stephen J Vesper; Linda Levin; Gurjit K Khurana Hershey; Shu Zheng; Patrick Ryan; Sergey A Grinshpun; Manuel Villareal; Grace Lemasters
Journal:  J Allergy Clin Immunol       Date:  2012-07-11       Impact factor: 10.793

9.  Mold exposure during infancy as a predictor of potential asthma development.

Authors:  Yulia Y Iossifova; Tiina Reponen; Patrick H Ryan; Linda Levin; David I Bernstein; James E Lockey; Gurjit K Khurana Hershey; Manuel Villareal; Grace LeMasters
Journal:  Ann Allergy Asthma Immunol       Date:  2009-02       Impact factor: 6.347

10.  Confirmed moisture damage at home, respiratory symptoms and atopy in early life: a birth-cohort study.

Authors:  Anne M Karvonen; Anne Hyvärinen; Marjut Roponen; Matthias Hoffmann; Matti Korppi; Sami Remes; Erika von Mutius; Aino Nevalainen; Juha Pekkanen
Journal:  Pediatrics       Date:  2009-07-27       Impact factor: 7.124

View more
  21 in total

Review 1.  School Environmental Intervention Programs.

Authors:  Perdita Permaul; Wanda Phipatanakul
Journal:  J Allergy Clin Immunol Pract       Date:  2018 Jan - Feb

Review 2.  School exposure and asthma.

Authors:  Brittany Esty; Wanda Phipatanakul
Journal:  Ann Allergy Asthma Immunol       Date:  2018-05       Impact factor: 6.347

3.  Allergens on desktop surfaces in preschools and elementary schools of urban children with asthma.

Authors:  Watcharoot Kanchongkittiphon; William J Sheehan; James Friedlander; Martin D Chapman; Eva-Maria King; Karine Martirosyan; Sachin N Baxi; Perdita Permaul; Jonathan M Gaffin; Lianne Kopel; Ann Bailey; Chunxia Fu; Carter R Petty; Diane R Gold; Wanda Phipatanakul
Journal:  Allergy       Date:  2014-04-18       Impact factor: 13.146

Review 4.  Asthma and Allergies in the School Environment.

Authors:  Brittany Esty; Perdita Permaul; Kristie DeLoreto; Sachin N Baxi; Wanda Phipatanakul
Journal:  Clin Rev Allergy Immunol       Date:  2019-12       Impact factor: 8.667

Review 5.  Social disadvantage and asthma control in children.

Authors:  Lianne S Kopel; Wanda Phipatanakul; Jonathan M Gaffin
Journal:  Paediatr Respir Rev       Date:  2014-05-16       Impact factor: 2.726

Review 6.  A Practical Approach to Severe Asthma in Children.

Authors:  Emily E Barsky; Lauren M Giancola; Sachin N Baxi; Jonathan M Gaffin
Journal:  Ann Am Thorac Soc       Date:  2018-04

Review 7.  Inner city asthma.

Authors:  Peter J Gergen; Alkis Togias
Journal:  Immunol Allergy Clin North Am       Date:  2014-10-18       Impact factor: 3.479

8.  Subchronic exposures to fungal bioaerosols promotes allergic pulmonary inflammation in naïve mice.

Authors:  A P Nayak; B J Green; A R Lemons; N B Marshall; W T Goldsmith; M L Kashon; S E Anderson; D R Germolec; D H Beezhold
Journal:  Clin Exp Allergy       Date:  2016-05-03       Impact factor: 5.018

Review 9.  Environmental remediation in the treatment of allergy and asthma: latest updates.

Authors:  Lakiea S Wright; Wanda Phipatanakul
Journal:  Curr Allergy Asthma Rep       Date:  2014-03       Impact factor: 4.806

Review 10.  Recent advances in environmental controls outside the home setting.

Authors:  Marissa Hauptman; Wanda Phipatanakul
Journal:  Curr Opin Allergy Clin Immunol       Date:  2016-04
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.