Literature DB >> 24102846

Obesity as a barrier to living kidney donation: a center-based analysis.

Mala Sachdeva1, Suzanne Sunday, Ezra Israel, Jeny Varghese, Lisa Rosen, Madhu Bhaskaran, Ernesto P Molmenti, Joseph Mattana.   

Abstract

BACKGROUND: Obesity is a major epidemic and may present a significant barrier to living kidney donation. The purpose of our study was to determine the frequency of obesity as an exclusion factor and assess how often these donors lose weight and donate.
METHODS: A single center, retrospective analysis of 104 potential living kidney donors between 2008 and 2012.
RESULTS: Of the 104 donors, 19 (18%) had a normal body mass index (BMI) of <25. Eighty-five of the 104 (82%) donors spanned the overweight to morbidly obese classifications. Thirty-eight (37%) were overweight (BMI 25-29.9). Twenty-four (23%) were categorized as class I obesity (BMI 30-34.9), 17 (16%) as class II obesity (BMI 35-39.9), and six (6%) as class III obesity (BMI >40). There were a total of 23 donors (22%) who were considered moderately and morbidly obese (BMI >35). Of these, only three (13%) succeeded at losing weight and donating.
CONCLUSIONS: Obesity may be a frequent barrier to living kidney donation, directly leading to exclusion as a potential kidney donor in about one in five instances. Successful weight loss leading to donation appears to be infrequent, suggesting need to address obesity in the donor population.
© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  donor; kidney; living; obesity; transplantation

Mesh:

Year:  2013        PMID: 24102846     DOI: 10.1111/ctr.12246

Source DB:  PubMed          Journal:  Clin Transplant        ISSN: 0902-0063            Impact factor:   2.863


  6 in total

1.  Donation approval among obese living kidney donor candidates: The impact of metabolic syndrome.

Authors:  Margaux N Mustian; Vineeta Kumar; Michael Hanaway; Paul A MacLennan; Brittany A Shelton; Rhiannon D Reed; Tanya Correya; Raynesha Grant; Alexis Carter; Gavin Baker; Jelecia Patterson; Markayla Peoples; Semaj Holden; Babak J Orandi; Jayme E Locke
Journal:  Surgery       Date:  2019-08-20       Impact factor: 3.982

2.  Initiating Maintenance Dialysis Before Living Kidney Donor Transplantation When a Donor Candidate Evaluation Is Well Underway.

Authors:  Steven Habbous; Eric McArthur; Stephanie N Dixon; Susan McKenzie; Carlos Garcia-Ochoa; Ngan N Lam; Krista L Lentine; Christine Dipchand; Kenneth Litchfield; Mehmet A Begen; Sisira Sarma; Amit X Garg
Journal:  Transplantation       Date:  2018-07       Impact factor: 4.939

3.  Weight trends in United States living kidney donors: Analysis of the UNOS database.

Authors:  Mala Sachdeva; Lisa M Rosen; Jeny Varghese; Steven Fishbane; Ernesto P Molmenti
Journal:  World J Transplant       Date:  2015-09-24

4.  Patient Perspectives on Weight Management for Living Kidney Donation.

Authors:  Margaux N Mustian; Michael Hanaway; Vineeta Kumar; Rhiannon D Reed; Brittany A Shelton; Raynesha Grant; Alexis Carter; Jayme E Locke
Journal:  J Surg Res       Date:  2019-07-03       Impact factor: 2.192

5.  The Efficiency of Evaluating Candidates for Living Kidney Donation: A Scoping Review.

Authors:  Steven Habbous; Justin Woo; Ngan N Lam; Krista L Lentine; Matthew Cooper; Marian Reich; Amit X Garg
Journal:  Transplant Direct       Date:  2018-09-20

Review 6.  Improving the outcome of kidney transplantation by ameliorating renal ischemia reperfusion injury: lost in translation?

Authors:  T C Saat; E K van den Akker; J N M IJzermans; F J M F Dor; R W F de Bruin
Journal:  J Transl Med       Date:  2016-01-20       Impact factor: 5.531

  6 in total

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