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Literature DB >> 24101102

Prevention: Polypills for cardiovascular prevention: a step forward?

Abstract

The effect of a fixed-dose combination drug strategy ('polypill') on patients' adherence to medication was analysed in a series of 2,004 individuals with, or at high risk of, cardiovascular disease in the UMPIRE study. The polypill improved adherence by >20%, but the reduction in blood-pressure and cholesterol levels was modest.

Entities: Chemical Disease Species

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Year: 2013 PMID： 24101102 DOI： 10.1038/nrcardio.2013.157

Source DB: PubMed Journal: Nat Rev Cardiol ISSN： 1759-5002 Impact factor: 32.419

10 in total

1. The availability and affordability of selected essential medicines for chronic diseases in six low- and middle-income countries.

Authors: Shanti Mendis; Keiko Fukino; Alexandra Cameron; Richard Laing; Anthonio Filipe; Oussama Khatib; Jerzy Leowski; Margaret Ewen
Journal: Bull World Health Organ Date: 2007-04 Impact factor: 9.408

2. Global public health: a scorecard.

Authors: Robert Beaglehole; Ruth Bonita
Journal: Lancet Date: 2008-10-20 Impact factor: 79.321

3. Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE Study): a prospective epidemiological survey.

Authors: Salim Yusuf; Shofiqul Islam; Clara K Chow; Sumathy Rangarajan; Gilles Dagenais; Rafael Diaz; Rajeev Gupta; Roya Kelishadi; Romaina Iqbal; Alvaro Avezum; Annamarie Kruger; Raman Kutty; Fernando Lanas; Liu Lisheng; Li Wei; Patricio Lopez-Jaramillo; Aytekin Oguz; Omar Rahman; Hany Swidan; Khalid Yusoff; Witold Zatonski; Annika Rosengren; Koon K Teo
Journal: Lancet Date: 2011-08-26 Impact factor: 79.321

Review 4. Maximizing therapeutic envelope for prevention of cardiovascular disease: role of polypill.

Authors: Ginés Sanz; Valentin Fuster
Journal: Mt Sinai J Med Date: 2012 Nov-Dec

5. Predictors of adherence with antihypertensive and lipid-lowering therapy.

Authors: Richard H Chapman; Joshua S Benner; Allison A Petrilla; Jonothan C Tierce; S Robert Collins; David S Battleman; J Sanford Schwartz
Journal: Arch Intern Med Date: 2005-05-23

6. The fixed-dose combination drug for secondary cardiovascular prevention project: improving equitable access and adherence to secondary cardiovascular prevention with a fixed-dose combination drug. Study design and objectives.

Authors: Ginés Sanz; Valentin Fuster; Luis Guzmán; Antonio Guglietta; Joan Albert Arnáiz; Felipe Martínez; Antonio Sarria; Maria Carla Roncaglioni; Kathryn Taubert
Journal: Am Heart J Date: 2011-11 Impact factor: 4.749

7. A strategy to reduce cardiovascular disease by more than 80%.

Authors: N J Wald; M R Law
Journal: BMJ Date: 2003-06-28

8. Multidimensional analysis of treatment adherence in patients with multiple chronic conditions. A cross-sectional study in a tertiary hospital.

Authors: Margarida Jansà; Carme Hernández; Mercè Vidal; Montse Nuñez; M Jesús Bertran; Sergi Sanz; Conxa Castell; Ginés Sanz
Journal: Patient Educ Couns Date: 2010-02-18

9. Effects of a fixed-dose combination strategy on adherence and risk factors in patients with or at high risk of CVD: the UMPIRE randomized clinical trial.

Authors: Simon Thom; Neil Poulter; Jane Field; Anushka Patel; Dorairaj Prabhakaran; Alice Stanton; Diederick E Grobbee; Michiel L Bots; K Srinath Reddy; Raghu Cidambi; Severine Bompoint; Laurent Billot; Anthony Rodgers
Journal: JAMA Date: 2013-09-04 Impact factor: 56.272

10. The efficacy and tolerability of 'polypills': meta-analysis of randomised controlled trials.

Authors: C Raina Elley; Ajay K Gupta; Ruth Webster; Vanessa Selak; Min Jun; Anushka Patel; Anthony Rodgers; Simon Thom
Journal: PLoS One Date: 2012-12-19 Impact factor: 3.240