Literature DB >> 2410069

In vitro culture of leukemic cells in t(4;11) acute leukemia.

R C Stong, J H Kersey.   

Abstract

In the present study we utilized a semisolid culture system with feeder cells and enriched media to evaluate the growth of acute leukemia associated with the 4;11 chromosomal translocation. We compared growth of t(4;11) leukemia to typical acute nonlymphocytic leukemia (ANL) and acute lymphocytic leukemia (ALL). The two cases of t(4;11) leukemia tested exhibited the highest cloning efficiency of cells tested. The growth characteristics of t(4;11) leukemia were more similar to ANL than ALL.

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Year:  1985        PMID： 2410069

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  8 in total

1.  Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.

Authors:  S Ziemin-van der Poel; N R McCabe; H J Gill; R Espinosa; Y Patel; A Harden; P Rubinelli; S D Smith; M M LeBeau; J D Rowley
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-01       Impact factor: 11.205

2.  A role for MEIS1 in MLL-fusion gene leukemia.

Authors:  Ashish R Kumar; Quanzhi Li; Wendy A Hudson; Weili Chen; Thien Sam; Qing Yao; Erik A Lund; Baolin Wu; Branden J Kowal; John H Kersey
Journal:  Blood       Date:  2008-12-24       Impact factor: 22.113

3.  Cloning of cDNAs of the MLL gene that detect DNA rearrangements and altered RNA transcripts in human leukemic cells with 11q23 translocations.

Authors:  N R McCabe; R C Burnett; H J Gill; M J Thirman; D Mbangkollo; M Kipiniak; E van Melle; S Ziemin-van der Poel; J D Rowley; M O Diaz
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-15       Impact factor: 11.205

4.  The (4;11)(q21;q23) chromosome translocations in acute leukemias involve the VDJ recombinase.

Authors:  Y Gu; G Cimino; H Alder; T Nakamura; R Prasad; O Canaani; D T Moir; C Jones; P C Nowell; C M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-01       Impact factor: 11.205

5.  Molecular rearrangements of the MLL gene are present in most cases of infant acute myeloid leukemia and are strongly correlated with monocytic or myelomonocytic phenotypes.

Authors:  P H Sorensen; C S Chen; F O Smith; D C Arthur; P H Domer; I D Bernstein; S J Korsmeyer; G D Hammond; J H Kersey
Journal:  J Clin Invest       Date:  1994-01       Impact factor: 14.808

6.  Heterogeneity of cultured leukemic lymphoid progenitor cells from B cell precursor acute lymphoblastic leukemia (ALL) patients.

Authors:  F M Uckun; J H Kersey; K J Gajl-Peczalska; N A Heerema; A J Provisor; D Haag; G Gilchrist; C W Song; D C Arthur; J Roloff
Journal:  J Clin Invest       Date:  1987-09       Impact factor: 14.808

7.  The Impact of Exosomes/Microvesicles Derived from Myeloid Dendritic Cells Cultured in the Presence of Calcitriol and Tacalcitol on Acute B-Cell Precursor Cell Lines with MLL Fusion Gene.

Authors:  Eliza Turlej; Tomasz Marek Goszczyński; Marek Drab; Beata Orzechowska; Magdalena Maciejewska; Joanna Banach; Joanna Wietrzyk
Journal:  J Clin Med       Date:  2022-04-15       Impact factor: 4.964

8.  Use of a novel colony assay to evaluate the cytotoxicity of an immunotoxin containing pokeweed antiviral protein against blast progenitor cells freshly obtained from patients with common B-lineage acute lymphoblastic leukemia.

Authors:  F M Uckun; K J Gajl-Peczalska; J H Kersey; L L Houston; D A Vallera
Journal:  J Exp Med       Date:  1986-02-01       Impact factor: 14.307
  8 in total

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