Literature DB >> 24096932

Seeking a MCL-1 inhibitor.

G Brumatti1, P G Ekert.   

Abstract

Entities:  

Mesh:

Substances:

Year:  2013        PMID: 24096932      PMCID: PMC3792435          DOI: 10.1038/cdd.2013.114

Source DB:  PubMed          Journal:  Cell Death Differ        ISSN: 1350-9047            Impact factor:   15.828


× No keyword cloud information.
  9 in total

1.  Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia.

Authors:  Stefan P Glaser; Erinna F Lee; Evelyn Trounson; Philippe Bouillet; Andrew Wei; W Douglas Fairlie; David J Izon; Johannes Zuber; Amy R Rappaport; Marco J Herold; Warren S Alexander; Scott W Lowe; Lorraine Robb; Andreas Strasser
Journal:  Genes Dev       Date:  2012-01-15       Impact factor: 11.361

2.  Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members.

Authors:  Michael Certo; Victoria Del Gaizo Moore; Mari Nishino; Guo Wei; Stanley Korsmeyer; Scott A Armstrong; Anthony Letai
Journal:  Cancer Cell       Date:  2006-05       Impact factor: 31.743

3.  The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

Authors:  Mark F van Delft; Andrew H Wei; Kylie D Mason; Cassandra J Vandenberg; Lin Chen; Peter E Czabotar; Simon N Willis; Clare L Scott; Catherine L Day; Suzanne Cory; Jerry M Adams; Andrew W Roberts; David C S Huang
Journal:  Cancer Cell       Date:  2006-11       Impact factor: 31.743

4.  Preclinical studies of TW-37, a new nonpeptidic small-molecule inhibitor of Bcl-2, in diffuse large cell lymphoma xenograft model reveal drug action on both Bcl-2 and Mcl-1.

Authors:  Ramzi M Mohammad; Anton Scott Goustin; Amro Aboukameel; Ben Chen; Sanjeev Banerjee; Guoping Wang; Zaneta Nikolovska-Coleska; Shaomeng Wang; Ayad Al-Katib
Journal:  Clin Cancer Res       Date:  2007-04-01       Impact factor: 12.531

5.  Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

Authors:  Joseph T Opferman; Hiromi Iwasaki; Christy C Ong; Heikyung Suh; Shin-ichi Mizuno; Koichi Akashi; Stanley J Korsmeyer
Journal:  Science       Date:  2005-02-18       Impact factor: 47.728

6.  Mcl-1 deficiency results in peri-implantation embryonic lethality.

Authors:  J L Rinkenberger; S Horning; B Klocke; K Roth; S J Korsmeyer
Journal:  Genes Dev       Date:  2000-01-01       Impact factor: 11.361

7.  An inhibitor of Bcl-2 family proteins induces regression of solid tumours.

Authors:  Tilman Oltersdorf; Steven W Elmore; Alexander R Shoemaker; Robert C Armstrong; David J Augeri; Barbara A Belli; Milan Bruncko; Thomas L Deckwerth; Jurgen Dinges; Philip J Hajduk; Mary K Joseph; Shinichi Kitada; Stanley J Korsmeyer; Aaron R Kunzer; Anthony Letai; Chi Li; Michael J Mitten; David G Nettesheim; ShiChung Ng; Paul M Nimmer; Jacqueline M O'Connor; Anatol Oleksijew; Andrew M Petros; John C Reed; Wang Shen; Stephen K Tahir; Craig B Thompson; Kevin J Tomaselli; Baole Wang; Michael D Wendt; Haichao Zhang; Stephen W Fesik; Saul H Rosenberg
Journal:  Nature       Date:  2005-05-15       Impact factor: 49.962

8.  Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.

Authors:  Simon N Willis; Lin Chen; Grant Dewson; Andrew Wei; Edwina Naik; Jamie I Fletcher; Jerry M Adams; David C S Huang
Journal:  Genes Dev       Date:  2005-05-18       Impact factor: 11.361

9.  The landscape of somatic copy-number alteration across human cancers.

Authors:  Rameen Beroukhim; Craig H Mermel; Dale Porter; Guo Wei; Soumya Raychaudhuri; Jerry Donovan; Jordi Barretina; Jesse S Boehm; Jennifer Dobson; Mitsuyoshi Urashima; Kevin T Mc Henry; Reid M Pinchback; Azra H Ligon; Yoon-Jae Cho; Leila Haery; Heidi Greulich; Michael Reich; Wendy Winckler; Michael S Lawrence; Barbara A Weir; Kumiko E Tanaka; Derek Y Chiang; Adam J Bass; Alice Loo; Carter Hoffman; John Prensner; Ted Liefeld; Qing Gao; Derek Yecies; Sabina Signoretti; Elizabeth Maher; Frederic J Kaye; Hidefumi Sasaki; Joel E Tepper; Jonathan A Fletcher; Josep Tabernero; José Baselga; Ming-Sound Tsao; Francesca Demichelis; Mark A Rubin; Pasi A Janne; Mark J Daly; Carmelo Nucera; Ross L Levine; Benjamin L Ebert; Stacey Gabriel; Anil K Rustgi; Cristina R Antonescu; Marc Ladanyi; Anthony Letai; Levi A Garraway; Massimo Loda; David G Beer; Lawrence D True; Aikou Okamoto; Scott L Pomeroy; Samuel Singer; Todd R Golub; Eric S Lander; Gad Getz; William R Sellers; Matthew Meyerson
Journal:  Nature       Date:  2010-02-18       Impact factor: 49.962

  9 in total
  5 in total

1.  Small molecule inhibitor TW-37 is tolerable and synergistic with chemotherapy in nasopharyngeal carcinoma.

Authors:  Ying Lu; Haixin Huang; Hui Yang; Dagui Chen; Sibei Wu; Zhou Jiang; Rensheng Wang
Journal:  Cell Cycle       Date:  2017-07-11       Impact factor: 4.534

2.  Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro.

Authors:  Jack D Bracken; Andrew D Carlson; James H Frederich; Mai Nguyen; Gordon C Shore; Patrick G Harran
Journal:  Tetrahedron Lett       Date:  2015-06-03       Impact factor: 2.415

3.  Phosphorylation alters Bim-mediated Mcl-1 stabilization and priming.

Authors:  Jason E Conage-Pough; Lawrence H Boise
Journal:  FEBS J       Date:  2018-05-29       Impact factor: 5.542

4.  Synergistic Effects of TW-37 and ABT-263 on Renal Cell Carcinoma Cells.

Authors:  Rui Yu; Yefen Lu; Ren Yu; Jianjun Xie; Shoujun Zhou
Journal:  Cancer Manag Res       Date:  2021-02-03       Impact factor: 3.989

5.  Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting.

Authors:  Erwin Pannecoucke; Maaike Van Trimpont; Johan Desmet; Tim Pieters; Lindy Reunes; Lisa Demoen; Marnik Vuylsteke; Stefan Loverix; Karen Vandenbroucke; Philippe Alard; Paula Henderikx; Sabrina Deroo; Franky Baatz; Eric Lorent; Sophie Thiolloy; Klaartje Somers; Yvonne McGrath; Pieter Van Vlierberghe; Ignace Lasters; Savvas N Savvides
Journal:  Sci Adv       Date:  2021-03-26       Impact factor: 14.136

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.