| Literature DB >> 24096138 |
C E Krafft1, J E Pierce2, N F Schwarz3, L Chi4, A L Weinberger5, D J Schaeffer6, A L Rodrigue7, J Camchong8, J D Allison9, N E Yanasak10, T Liu11, C L Davis12, J E McDowell13.
Abstract
Children with low aerobic fitness have altered brain function compared to higher-fit children. This study examined the effect of an 8-month exercise intervention on resting state synchrony. Twenty-two sedentary, overweight (body mass index ≥85th percentile) children 8-11 years old were randomly assigned to one of two after-school programs: aerobic exercise (n=13) or sedentary attention control (n=9). Before and after the 8-month programs, all subjects participated in resting state functional magnetic resonance imaging scans. Independent components analysis identified several networks, with four chosen for between-group analysis: salience, default mode, cognitive control, and motor networks. The default mode, cognitive control, and motor networks showed more spatial refinement over time in the exercise group compared to controls. The motor network showed increased synchrony in the exercise group with the right medial frontal gyrus compared to controls. Exercise behavior may enhance brain development in children.Entities:
Keywords: AFNI; ANOVA; Analysis of Functional Neuroimages; BOLD; CAS; CC; Cognitive Assessment System; DMN; FMRIB Software Libraries; FOV; FSL; ICA; Independent Component Analysis; MNI; Montreal Neurological Institute; RSNs; TE; TR; aerobic exercise; analysis of variance; blood oxygenation level-dependent; cognitive control; default mode; default mode network; development; echo time; fMRI; field of view; functional magnetic resonance imaging; obesity; repetition time; resting state fMRI; resting state networks; rsfMRI
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Year: 2013 PMID： 24096138 PMCID： PMC3995346 DOI： 10.1016/j.neuroscience.2013.09.052
Source DB: PubMed Journal: Neuroscience ISSN： 0306-4522 Impact factor: 3.590