| Literature DB >> 24090976 |
Andrés J M Ferreri1, Silvia Govi, Maurilio Ponzoni.
Abstract
A link with infectious agents, bacteria and viruses in particular, has been reported for many lymphoma entities. Marginal zone lymphomas (extranodal, nodal and splenic forms) are frequently associated with chronic infections, with important clinical, molecular, biological, and therapeutic implications. The well-known correlation between Helicobacter pylori and gastric MALT-lymphoma, the recently reported links between Chlamydophila psittaci and ocular adnexal MALT-lymphoma and Borrelia burgdorferi and cutaneous MALT lymphoma constitute the best studied examples of lymphomagenic activity of bacteria, while the hepatitis C virus represents the most extensively investigated virus associated with marginal zone lymphomas. Biological and clinical features, therapeutic implications and future perspectives of these lymphoma-microbial associations are discussed in this review.Entities:
Keywords: Borrelia; Chlamydophila psittaci; Helicobacter pylori; Hepatitis C virus; Lymphomagenesis; MALT-type lymphoma; Marginal zone lymphomas
Mesh：
Year: 2013 PMID： 24090976 DOI： 10.1016/j.semcancer.2013.09.004
Source DB: PubMed Journal: Semin Cancer Biol ISSN： 1044-579X Impact factor: 15.707