| Literature DB >> 24090410 |
Aigang Yang1, Longlong Si, Zhenping Shi, Li Tian, Dong Liu, Demin Zhou, Peter Proksch, Wenhan Lin.
Abstract
Chemical examination of an arctic actinomycete Streptomyces nitrosporeus resulted in the isolation of two new alkaloids named nitrosporeusines A (1) and B (2), an unprecedented skeleton containing benzenecarbothioc cyclopenta[c]pyrrole-1,3-dione. Their structures were determined through extensive spectroscopic analyses in association with X-ray single crystal diffraction. Both 1 and 2 exhibited inhibitory activities against the H1N1 virus in MDCK cells.Entities:
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Year: 2013 PMID： 24090410 DOI： 10.1021/ol4026809
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005